Protein Alignment brp and erc1b

DIOPT Version :9

• Sequence 1: NP_001246228.1
• Gene: brp / 35977
• FlyBaseID: FBgn0259246
• Length: 2238
• Species: Drosophila melanogaster
• Sequence 2: XP_021330884.1
• Gene: erc1b / 560003
• ZFINID: ZDB-GENE-041210-51
• Length: 1136
• Species: Danio rerio
• Alignment Length: 1627
• Identity: 335/1627 - (20%)
• Similarity: 604/1627 - (37%)
• Gaps: 608/1627 - (37%)

  Fly    10 TSSGVRSPGRVRRLQELPTVDRSPSRDYG------APRGSPLAM-------------GSPYYRDM 55
            ||...:||||..||...|.:....:...|      .|.|..|:|             |..|..|.
Zfish    16 TSGSTQSPGRSPRLPRSPRLGHRRTNSTGGSGAGAGPGGKTLSMENIQSLNAAYATSGPMYMSDN 80

  Fly    56 DEPTS------------------PAGA-----GHHRSRSASRPPMAHAMDY-----PRTRYQSLD 92
            :..||                  |.|.     |...:.:...|....|:.:     |.|...::
Zfish    81 EVVTSGPDLPKSTMTLGRTGGRVPYGVRTTVMGSSPNIATGSPGTTDAIAFGDHHMPSTLASTV- 144

  Fly    93 RGGLVDPHDREFIPIREPRDRSRDRSLERGLYLEDELYGRSARQSPSAMGGYNTGMGPTSDRAYL 157
                  ||.     :|:.||                                ||.|
Zfish   145 ------PHS-----LRQARD--------------------------------NTIM--------- 157

  Fly   158 GDLQHQNTDLQRELGNLKRELELTNQKLGSSMHSIKTFWSPELKKERALRKEESAKYSLINDQLK 222
             |||.|..::.||...|::|:::...||.|||:||||||||||||||||||:|::|.|:..:|.:
Zfish   158 -DLQTQLKEVLRENELLRKEVDVKESKLSSSMNSIKTFWSPELKKERALRKDEASKISVWKEQYR 221

  Fly   223 LLSTENQKQAMLVRQLEEELRLRMRQPNLEMQQ-----------------QMEAIYAENDHLQRE 270
            ::..|||...|.::.|::|||:: |..|...||                 ..:.::.|::...:|
Zfish   222 VVQDENQHLQMTIQALQDELRIQ-RDLNQLFQQDPSSRPGEPLTAELTEENFQRLHGEHERQAKE 285

  Fly   271 ISILRETIKDLECRVETQKQTLIARDESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQMYNNY 335
            :.:||:|::::|.|::||||||.||||||||||||||:||:..:...:..::.:.:|..:|:.::
Zfish   286 LFLLRKTLEEMELRIDTQKQTLNARDESIKKLLEMLQSKGLSAKASEEDHERTRRLADAEMHIHH 350

  Fly   336 TGASGSSPPLPDIIGQYYGPGSLGPGPLSYGSGNGYGPPGYDLYGPSTSTAAGGYGLYDPQIYGP 400
                                                                             
Zfish   351 ----------------------------------------------------------------- 350

  Fly   401 CQQTSPIRRRRYSIAGLPSATMYNDVYGYPAPPLQQTSSSNIVNLLNEAHKSISRSSQILNLTNQ 465
                                                     :.:||::..|.
Zfish   351 -----------------------------------------LESLLDQRDKE------------- 361

  Fly   466 ARQLGQLVTTPLGGGGVGMGLGRVVSSYPTLHPGDTSPPYLNDNLMQMSTSFSSQPNMYFQPQAQ 530
                              |||                   |.::|.:....         .|::.
Zfish   362 ------------------MGL-------------------LREDLHRRYEG---------APESA 380

  Fly   531 VQQVLPTQLTAAQSAAAAAAR-LRPAYSVTNLVSSYPTTTAAGYGCKYGGYGNPYQSDLGYGNPL 594
            ..:.|.|.:....|...:..| ||.......::.|                          ...|
Zfish   381 KTKALQTVIEMKDSKIGSMERSLRDLEDEIQMLKS--------------------------NGAL 419

  Fly   595 APFQQRQLMAHQSLHASNPAISQYYQNQGAATGTGASAAALAYNLQQQFAGTQHYGGGSQGPPLG 659
            :..::.:.|....::.|:   |::.:|:             ...|:.:.|.:|     :||..|
Zfish   420 STEEREEEMKQMEVYRSH---SKFMKNK-------------VEQLKDELAQSQ-----TQGEEL- 462

  Fly   660 HSHIQASVQQQMHPQYQYHVHQHQNHLQTHPLAALANTSGPFGGTLASSARDYVDGLHHAAHSHT 724
                                                                             
Zfish   463 ----------------------------------------------------------------- 462

  Fly   725 HPHSHPHHSSHHSHHTAYPHSHSHHQQQQPHQAHHHHHLPYSKLDLDYPKLPQEHKRQLDEFRLE 789
                                                            .|...|.::::|:.:.:
Zfish   463 ------------------------------------------------KKRVSELQQEIDQVKQD 479

  Fly   790 IQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIE 854
            :.|:|.|:|.:..|::||..|..|.::|:.||||||.|||:...:|||:|:.:|.|||||...:.
Zfish   480 LSRKDSELLGLQTKLETLTNQFSDSKQHVDVLKESLTAKEQRAAILQTEVDALRLRLEEKEATLN 544

  Fly   855 KKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAM 919
            ||::...:..:|:..|..|:.:|||.:|:|:||::|||:|||||::.||:|:.|:...:.|:.::
Zfish   545 KKSKQIQEVSEEKGTLNGEIHDLKDMLDVKERKVNVLQKKIENLQEQLKDKEKQMSSLKERVKSL 609

  Fly   920 QAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVE 984
            ||..|:::.||::||||:.:||:.:.:|::||||.|.||.||.:.:::|:.:.|.|:...:.:
Zfish   610 QADTSNTDTALSTLEEALAEKERIIERLKEQRDRDEREKSEELESNKKELKELKEKVNVLQGD-- 672

  Fly   985 KLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERL 1049
                     :::||...:.|:...|.|..|..:.:                 .::..||:..|:.
Zfish   673 ---------LSDREASLLDLKEHASSLASSGLKKD-----------------SKLKSLEIALEQK 711

  Fly  1050 KHDLERSQNVQKLMFETGKISTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAER 1114
            |.:..:.::                           :.::|:|..|..           .|:|..
Zfish   712 KEECIKLES---------------------------QLKKRSDLVSGH-----------PSNAHS 738

  Fly  1115 AREEA---AALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVE 1176
            ...||   |.|.|::...:.||.|.|.....||.|.:.|.:.|.:.::..:    |:||..:|:|
Zfish   739 VAVEAQTSAGLSERIATLEQEVARYKEDAGKAQAEVDRLLEILREMENEKN----DKDRKINELE 799

  Fly  1177 -----KIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTY 1236
                 ::|::.::......|.|::..|....:::|:...|::.:...:.          |:.|..
Zfish   800 SMTSRQMKDQSKKVANLKHKEQVEKNKNAQLMEEARKREDNINESSQQV----------KDSLRL 854

  Fly  1237 DYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERS 1301
            ..|.:: :|::||.::.::..|||.:....:..|...||   |:..:....::...|||::|.:.
Zfish   855 KDDRIE-ELEEALRESVQITAEREMVLAQEESARANAEK---QMEELLAAMEKVKQELESMKAKL 915

  Fly  1302 ESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQK 1366
            .|.|    ::..::|:..|.|     |.|:...:::.|:|:::               ||.|:
Zfish   916 SSTQ----QSLAEKESHLTTL-----RAERRKHLEEVLEMKQE---------------ALLAA-- 954

  Fly  1367 LIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAE---RSGLAASKAREDLR 1428
             |.|||.:....|....|..:.|:|:..|:     .|.||...:::.:   |..|.|....:|..
Zfish   955 -ISEKDANIALLELSSSKKKKTQDEVALLK-----REKDRLVHQLKQQTQNRMKLMADNYEDDHH 1013

  Fly  1429 KLQD-ESTRLQEACDRAALQLSRAKECEDNARSELE----------HSRD-----------RFDK 1471
            |..: :.|..:.:.|:....|.   :...| ||:|:          |.||           .:.:
Zfish  1014 KASNSDQTNHKPSPDQIIPPLI---DLNQN-RSKLKLYIGHLTALCHERDPLILQDLAPPSAYHR 1074

  Fly  1472 LQTDIRRAQGEK---EHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYE 1533
            .|.|....:.:|   |..:||||    :.||..|...:.:.||  .::.|.|....||::.:..|
Zfish  1075 SQRDAWEEELQKMSPEQLESELE----QCERESAELQEYANSV--LQQIADHCPDILEQVVNALE 1133

  Fly  1534 KS 1535
            :|
Zfish  1134 ES 1135

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brp	NP_001246228.1	KRTAP	332..401	CDD:256601	0/68 (0%)
		Myosin_tail_1	789..1824	CDD:279860	193/783 (25%)
		SMC_prok_B	1509..>2215	CDD:274008	8/27 (30%)
		Bud13	2091..>2157	CDD:286779
erc1b	XP_021330884.1	Cast	160..1003	CDD:313412	266/1285 (21%)
		SMC_N	851..>1108	CDD:330553	66/300 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4809
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	362	1.000	Inparanoid score	I2153
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002038
OrthoInspector	1	1.000	-	-		oto39217
orthoMCL	1	0.900	-	-		OOG6_104556
Panther	1	1.100	-	-	O	PTHR18861
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3525
SonicParanoid	1	1.000	-	-		X1708
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.890