DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment brp and erc2

DIOPT Version :9

Sequence 1:	NP_001246228.1	Gene:	brp / 35977	FlyBaseID:	FBgn0259246	Length:	2238	Species:	Drosophila melanogaster
Sequence 2:	XP_021334189.1	Gene:	erc2 / 101883379	-ID:	-	Length:	509	Species:	Danio rerio

Alignment Length:	485	Identity:	136/485 - (28%)
Similarity:	240/485 - (49%)	Gaps:	91/485 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   747 SHHQQQQPHQAHHHHHLPYSKLDLDYPKLPQEHKRQLDEFRLEIQRRDQEILAMAAKMKTLEEQH 811
            ||.::.:..:.:.:|    ||.          .|.::|..:.|:.:::.|::|:..|:.||..|:
Zfish    84 SHGEEFRQMEVYKNH----SKF----------MKNKIDLLKQEVVKKESELMALQTKLDTLTNQN 134

  Fly   812 QDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTE 876
            .|.::||.||||||.|||....:|||:||.:|.|:||:...:.||.:.....::|:..|:||:.:
Zfish   135 SDSKKHIEVLKESLTAKEHRSCILQTEVEALRLRVEERESFLNKKNKQIQDLIEEKATLSSEICD 199

  Fly   877 LKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKE 941
            |||.:|:|::|||:||:|:|||...|||:|.|:.....|:|::||..|:::.||.:||||:..|.
Zfish   200 LKDMLDVKEKKISILQKKLENLAQQLKERDTQLVSLELRVSSLQADSSNTDSALITLEEALSQKI 264

  Fly   942 KQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRL-ERAVTERER------ 999
            ::          ||.:|.|..:|               :|::..||.|| |:...:.:|
Zfish   265 EE----------AEMQKNENNEL---------------KSKLASLQQRLSEKQACDSDRVSGWSP 304

  Fly  1000 -LEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQRIARL--ELENERLKHDLERSQNVQK 1061
             |..:|:..|:|....:.||:|:..|:           ||:..|  :|::|||:.|....|..::
Zfish   305 DLSERLQILQTEASGHQEELQKSHSEL-----------QRVTDLLRDLQSERLQQDNRIIQMERQ 358

  Fly  1062 LMFETGKISTT---FGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQ 1123
            |..::.|.|.:   .|.|:..|.::||......||...||...:..|.|:||.......|.:.::
Zfish   359 LKEQSQKQSVSPGQAGETSPNTQRQLDDLLSALDKTRKELDVVRQRLSVSQSSLSERDNELSRIR 423

  Fly  1124 EKLEKSQGEVYRLKAKLENAQGEQE--SLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQ 1186
            .:..|...|:.:||    |....::  :||:|.|:..:...::|       |.::.:.|..|.
Zfish   424 AEHSKQLSEILQLK----NMSSPEDVMTLRREKERFINHQKQVH-------SRMKPMAEHYED-- 475

  Fly  1187 ATLGKSQLQHEKLQNSLDKAQNEVDHLQDK 1216
                    :|...|.|     :...|:|::
Zfish   476 --------EHIHAQYS-----HHPQHMQER 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brp	NP_001246228.1	KRTAP	332..401	CDD:256601
		Myosin_tail_1	789..1824	CDD:279860	129/443 (29%)
		SMC_prok_B	1509..>2215	CDD:274008
		Bud13	2091..>2157	CDD:286779
erc2	XP_021334189.1	SMC_N	<14..467	CDD:330553	129/443 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D187649at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010