Protein Alignment Wnt2 and WNT5B

DIOPT Version :9

• Sequence 1: NP_476810.1
• Gene: Wnt2 / 35975
• FlyBaseID: FBgn0004360
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: XP_024304971.1
• Gene: WNT5B / 81029
• HGNCID: 16265
• Length: 411
• Species: Homo sapiens
• Alignment Length: 334
• Identity: 145/334 - (43%)
• Similarity: 196/334 - (58%)
• Gaps: 31/334 - (9%)

  Fly    29 LCGRIPGLTPGQRNMCREMPDALIALGEGHQLGAQECQHQFRGHRWNCSEVWQRNVFAHVIPTAS 93
            :|.::|||:||||.:|:...:.:..:|||.:.|.:|||||||..|||||.....:||..|:...|
Human    99 VCSQLPGLSPGQRKLCQLYQEHMAYIGEGAKTGIKECQHQFRQRRWNCSTADNASVFGRVMQIGS 163

  Fly    94 REAAYTYAIASAGAAYAVTAACARGNISTCGCD--VRHKATPTGGGTPDEPWKWGGCSADVDFGM 156
            ||.|:|:|:::||...|::.||..|.:|||||.  .|.|..|       ..|.||||..:|::|.
Human   164 RETAFTHAVSAAGVVNAISRACREGELSTCGCSRTARPKDLP-------RDWLWGGCGDNVEYGY 221

  Fly   157 RYARRFMDARELERD--------SRTLMNLHNNRAGRTLVKKMLRTDCKCHGVSGSCVMKTCWKS 213
            |:|:.|:||||.|::        .|.||||.||.|||..|.||....||||||||||.:||||..
Human   222 RFAKEFVDAREREKNFAKGSEEQGRVLMNLQNNEAGRRAVYKMADVACKCHGVSGSCSLKTCWLQ 286

  Fly   214 LPPFRLVGDRLMLKYQKAKTVQAVKGKRGLRLVLSRKKHAGTARAQKPVLDWPKRMELIYLEASP 278
            |..||.|||||..||..|..::..: |..|.||.||             ...|...:|:|::.||
Human   287 LAEFRKVGDRLKEKYDSAAAMRVTR-KGRLELVNSR-------------FTQPTPEDLVYVDPSP 337

  Fly   279 NYCERSLQTGSQGTSGRTCQRTGHGPQSCDLLCCGRGHNTQHIRRTTQCRCQFRWCCEVKCDECD 343
            :||.|:..|||.||.||.|.:|..|...|:|:|||||:|.....:..:|.|:|.|||.|:|.:|.
Human   338 DYCLRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYNQFKSVQVERCHCKFHWCCFVRCKKCT 402

  Fly   344 ESYEEFTCK 352
            |..:::.||
Human   403 EIVDQYICK 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt2	NP_476810.1	wnt	36..352	CDD:278536	140/325 (43%)
WNT5B	XP_024304971.1	wnt	102..411	CDD:306592	142/329 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152284
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40508
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X108
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.740