Protein Alignment Wnt2 and WNT10B

DIOPT Version :10

• Sequence 1: NP_476810.1
• Gene: Wnt2 / 35975
• FlyBaseID: FBgn0004360
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_003385.2
• Gene: WNT10B / 7480
• HGNCID: 12775
• Length: 389
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 129/363 - (35%)
• Similarity: 183/363 - (50%)
• Gaps: 51/363 - (14%)

  Fly    25 TSVMLCGRIPGLTPGQRNMCREMPDALIALGEGHQLGAQECQHQFRGHRWNCSEVWQRNVFAH-- 87
            |:..:|..:.||:..|..:|...||...:..:|..:...|||||.|..|||||.:.......|
Human    43 TANTVCLTLSGLSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGGGRLPHHS 107

  Fly    88 -VIPTASREAAYTYAIASAGAAYAVTAACARGNISTCGCDVR----------------------- 128
             ::....||:|:::::.:||..:||..||:.|.:.:|||..:
Human   108 AILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALSRGKS 172

  Fly   129 --HKATPTGGGT-----PDEPWKWGGCSADVDFGMRYARRFMDARELERDSRTLMNLHNNRAGRT 186
              |.....|.|:     |.:.|:||||:.|:|||.:::|.|:|:||..||.:..|.:||||.||.
Human   173 FPHSLPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAPRDIQARMRIHNNRVGRQ 237

  Fly   187 LVKKMLRTDCKCHGVSGSCVMKTCWKSLPPFRLVGDRLMLKYQKAKTVQAVKGKRGLRLVLSRKK 251
            :|.:.|:..|||||.||||..||||::.|.||.||..|..:..:|..:..
Human   238 VVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRERLGRAIFIDT--------------- 287

  Fly   252 HAGTARAQKPVLDWPKRM--ELIYLEASPNYCERSLQTGSQGTSGRTCQRTGHGPQSCDLLCCGR 314
            |...:.|.:|.|. |:|:  ||:|.|.||::|||....||.||.||.|.:|......|..|||||
Human   288 HNRNSGAFQPRLR-PRRLSGELVYFEKSPDFCERDPTMGSPGTRGRACNKTSRLLDGCGSLCCGR 351

  Fly   315 GHNTQHIRRTTQCRCQFRWCCEVKCDECDESYEEFTCK 352
            |||.....|..:|.|:|.|||.|.||||..:.....||
Human   352 GHNVLRQTRVERCHCRFHWCCYVLCDECKVTEWVNVCK 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt2	NP_476810.1	Wnt_Wnt7	29..352	CDD:381713	126/357 (35%)
WNT10B	NP_003385.2	Wnt_Wnt10b	45..389	CDD:381730	126/359 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..197		5/25 (20%)