Protein Alignment Wnt2 and WNT8B

DIOPT Version :10

• Sequence 1: NP_476810.1
• Gene: Wnt2 / 35975
• FlyBaseID: FBgn0004360
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_003384.2
• Gene: WNT8B / 7479
• HGNCID: 12789
• Length: 351
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 118/310 - (38%)
• Similarity: 161/310 - (51%)
• Gaps: 29/310 - (9%)

  Fly    53 ALGEGHQLGAQECQHQFRGHRWNCSEVWQRNVFAHVIPTASREAAYTYAIASAGAAYAVTAACAR 117
            ::..|.|.|.:||::||...||||.|...:......:.:|:||.|:.:||:|||..|.:|..|:.
Human    42 SVAAGAQSGIEECKYQFAWDRWNCPERALQLSSHGGLRSANRETAFVHAISSAGVMYTLTRNCSL 106

  Fly   118 GNISTCGCDVRHKATPTGGGTPDEPWKWGGCSADVDFGMRYARRFMDARELERDSRTLMNLHNNR 182
            |:...||||........|.|     |.|||||.:|.||...:::|:||.|..:|:|..||||||.
Human   107 GDFDNCGCDDSRNGQLGGQG-----WLWGGCSDNVGFGEAISKQFVDALETGQDARAAMNLHNNE 166

  Fly   183 AGRTLVKKMLRTDCKCHGVSGSCVMKTCWKSLPPFRLVGDRLMLKYQKAKTVQAVKGKRGLRLVL 247
            |||..||..::..||||||||||..:|||..||.||.||..|..||..|..|..::|
Human   167 AGRKAVKGTMKRTCKCHGVSGSCTTQTCWLQLPEFREVGAHLKEKYHAALKVDLLQG-------- 223

  Fly   248 SRKKHAGTARAQKPVLDWPKR----MELIYLEASPNYCERSLQTGSQGTSGRTCQRTGHG----- 303
                 ||.:.|.:..:....|    .||::||.||:||..:...|..||.||.|.|.|..
Human   224 -----AGNSAAGRGAIADTFRSISTRELVHLEDSPDYCLENKTLGLLGTEGRECLRRGRALGRWE 283

  Fly   304 PQSCDLLC--CGRGHNTQHIRRTTQCRCQFRWCCEVKCDECDESYEEFTC 351
            .:||..||  ||.....:.....:.|.|:|.|||.|:|::|.....::.|
Human   284 RRSCRRLCGDCGLAVEERRAETVSSCNCKFHWCCAVRCEQCRRRVTKYFC 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt2	NP_476810.1	Wnt_Wnt7	29..352	CDD:381713	118/310 (38%)
WNT8B	NP_003384.2	Wnt_Wnt8b	30..334	CDD:381726	118/310 (38%)