Protein Alignment Wnt2 and WNT6

DIOPT Version :9

• Sequence 1: NP_476810.1
• Gene: Wnt2 / 35975
• FlyBaseID: FBgn0004360
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_006513.1
• Gene: WNT6 / 7475
• HGNCID: 12785
• Length: 365
• Species: Homo sapiens
• Alignment Length: 371
• Identity: 147/371 - (39%)
• Similarity: 192/371 - (51%)
• Gaps: 45/371 - (12%)

  Fly     8 LLIYIL---------WIMEIRLVSSFTSVMLCGRIPGLTPGQRNMCREMPDALIALGEGHQLGAQ 63
            ||:.:|         |.:...||...||:  |.:...|...|..:|:..|:.:..|..|.:||.:
Human    12 LLLLLLCPAHVGGLWWAVGSPLVMDPTSI--CRKARRLAGRQAELCQAEPEVVAELARGARLGVR 74

  Fly    64 ECQHQFRGHRWNCSEVWQRNVFAHVIPTASREAAYTYAIASAGAAYAVTAACARGNISTCGCDV- 127
            |||.|||..|||||.  ....|..::....||.|:.:||.:|||::|||.||:.|.:..|||..
Human    75 ECQFQFRFRRWNCSS--HSKAFGRILQQDIRETAFVFAITAAGASHAVTQACSMGELLQCGCQAP 137

  Fly   128 RHKATPTGGGTPDEP--------------WKWGGCSADVDFGMRYARRFMDAREL--ERDSRTLM 176
            |.:|.|...|.|..|              |:||||..|||||...:|.|||||..  ..|.|.|:
Human   138 RGRAPPRPSGLPGTPGPPGPAGSPEGSAAWEWGGCGDDVDFGDEKSRLFMDARHKRGRGDIRALV 202

  Fly   177 NLHNNRAGRTLVKKMLRTDCKCHGVSGSCVMKTCWKSLPPFRLVGDRLMLKYQKAKTVQAVK-GK 240
            .||||.|||..|:...||:|||||:||||.::|||:.|||||.||.||:.::..|..|.... ||
Human   203 QLHNNEAGRLAVRSHTRTECKCHGLSGSCALRTCWQKLPPFREVGARLLERFHGASRVMGTNDGK 267

  Fly   241 RGLRLVLSRKKHAGTARAQKPVLDWPKRMELIYLEASPNYCERSLQTGSQGTSGRTCQRTGHGPQ 305
            ..|..|          |..||    |.|.:|:|...||::|..:.:|||.||.||.|..:.....
Human   268 ALLPAV----------RTLKP----PGRADLLYAADSPDFCAPNRRTGSPGTRGRACNSSAPDLS 318

  Fly   306 SCDLLCCGRGHNTQHIRRTTQCRCQFRWCCEVKCDECDESYEEFTC 351
            .||||||||||..:.::....|.|:|.|||.|:|..|....|...|
Human   319 GCDLLCCGRGHRQESVQLEENCLCRFHWCCVVQCHRCRVRKELSLC 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt2	NP_476810.1	wnt	36..352	CDD:278536	138/334 (41%)
WNT6	NP_006513.1	wnt	47..364	CDD:278536	137/332 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..164		5/23 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810