Protein Alignment Wnt2 and WNT2

DIOPT Version :9

• Sequence 1: NP_476810.1
• Gene: Wnt2 / 35975
• FlyBaseID: FBgn0004360
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_003382.1
• Gene: WNT2 / 7472
• HGNCID: 12780
• Length: 360
• Species: Homo sapiens
• Alignment Length: 343
• Identity: 145/343 - (42%)
• Similarity: 213/343 - (62%)
• Gaps: 25/343 - (7%)

  Fly    14 WIMEIRLVSSFTSVMLCGRIPGLTPGQRNMCREMPDALIALGEGHQLGAQECQHQFRGHRWNCSE 78
            |.|.   .:..:|.::|..:|||...||.:|...||.:.|:.:|......|||||||.|||||:.
Human    28 WYMR---ATGGSSRVMCDNVPGLVSSQRQLCHRHPDVMRAISQGVAEWTAECQHQFRQHRWNCNT 89

  Fly    79 V-WQRNVFAHVIPTASREAAYTYAIASAGAAYAVTAACARGNISTCGCDVRHKATPTGGGTPDEP 142
            : ...::|..|:..:|||:|:.|||:|||..:|:|.||::|.:.:|.||.:..     |...|..
Human    90 LDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGEVKSCSCDPKKM-----GSAKDSK 149

  Fly   143 --WKWGGCSADVDFGMRYARRFMDARELE-RDSRTLMNLHNNRAGRTLVKKMLRTDCKCHGVSGS 204
              :.|||||.::|:|:::||.|:||:|.: :|:|.|||||||||||..||:.|:.:|||||||||
Human   150 GIFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGS 214

  Fly   205 CVMKTCWKSLPPFRLVGDRLMLKYQKAKTVQAVKGKRGLRLVLSRKKHAGTARAQKPVLDWPKRM 269
            |.::|||.::..||..||.|..||..|  :|.|..:.|....::.:      |.:||.     :.
Human   215 CTLRTCWLAMADFRKTGDYLWRKYNGA--IQVVMNQDGTGFTVANE------RFKKPT-----KN 266

  Fly   270 ELIYLEASPNYCERSLQTGSQGTSGRTCQRTGHGPQSCDLLCCGRGHNTQHIRRTTQCRCQFRWC 334
            :|:|.|.||:||.|..:.||.||:||.|..|..|..||:::|||||::|.|:.|.|:|.|:|.||
Human   267 DLVYFENSPDYCIRDREAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVTRMTKCGCKFHWC 331

  Fly   335 CEVKCDECDESYEEFTCK 352
            |.|:|.:|.|:.:..|||
Human   332 CAVRCQDCLEALDVHTCK 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt2	NP_476810.1	wnt	36..352	CDD:278536	137/319 (43%)
WNT2	NP_003382.1	wnt	43..349	CDD:306592	139/323 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152278
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326151at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X108
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750