Protein Alignment Wnt2 and Wnt5a

DIOPT Version :10

• Sequence 1: NP_476810.1
• Gene: Wnt2 / 35975
• FlyBaseID: FBgn0004360
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: XP_063131762.1
• Gene: Wnt5a / 64566
• RGDID: 69250
• Length: 391
• Species: Rattus norvegicus
• Alignment Length: 334
• Identity: 142/334 - (42%)
• Similarity: 195/334 - (58%)
• Gaps: 31/334 - (9%)

  Fly    29 LCGRIPGLTPGQRNMCREMPDALIALGEGHQLGAQECQHQFRGHRWNCSEVWQRNVFAHVIPTAS 93
            ||.::.||:.||:.:|....|.:..:|||.:.|.:|||:|||..|||||.|...:||..|:...|
  Rat    79 LCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDNTSVFGRVMQIGS 143

  Fly    94 REAAYTYAIASAGAAYAVTAACARGNISTCGCD--VRHKATPTGGGTPDEPWKWGGCSADVDFGM 156
            ||.|:|||:::||...|::.||..|.:|||||.  .|.|..|       ..|.||||..::|:|.
  Rat   144 RETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLP-------RDWLWGGCGDNIDYGY 201

  Fly   157 RYARRFMDARELER--------DSRTLMNLHNNRAGRTLVKKMLRTDCKCHGVSGSCVMKTCWKS 213
            |:|:.|:||||.||        .:|.|||||||.|||..|..:....||||||||||.:||||..
  Rat   202 RFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKCHGVSGSCSLKTCWLQ 266

  Fly   214 LPPFRLVGDRLMLKYQKAKTVQAVKGKRGLRLVLSRKKHAGTARAQKPVLDWPKRMELIYLEASP 278
            |..||.|||.|..||..|..::.  ..||..:.::.:.::            |...:|:|::.||
  Rat   267 LADFRKVGDALKEKYDSAAAMRL--NSRGKLVQVNSRFNS------------PTTQDLVYIDPSP 317

  Fly   279 NYCERSLQTGSQGTSGRTCQRTGHGPQSCDLLCCGRGHNTQHIRRTTQCRCQFRWCCEVKCDECD 343
            :||.|:..|||.||.||.|.:|..|...|:|:|||||::.....:|.:|.|:|.|||.|||.:|.
  Rat   318 DYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFHWCCYVKCKKCT 382

  Fly   344 ESYEEFTCK 352
            |..::|.||
  Rat   383 EIVDQFVCK 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt2	NP_476810.1	Wnt_Wnt7	29..352	CDD:381713	140/332 (42%)
Wnt5a	XP_063131762.1	None