Protein Alignment Wnt2 and WNT4

DIOPT Version :9

• Sequence 1: NP_476810.1
• Gene: Wnt2 / 35975
• FlyBaseID: FBgn0004360
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: XP_011539899.1
• Gene: WNT4 / 54361
• HGNCID: 12783
• Length: 373
• Species: Homo sapiens
• Alignment Length: 350
• Identity: 139/350 - (39%)
• Similarity: 201/350 - (57%)
• Gaps: 36/350 - (10%)

  Fly    14 WIMEIRLVSSFTSVMLCGRIPGLTPGQRNMCREMPDALIALGEGHQLGAQECQHQFRGHRWNCSE 78
            ::.::..|.|.:....|.::.||...|..||:...:.:.::..|.||..:|||:|||..|||||.
Human    49 YLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCST 113

  Fly    79 VWQRNVFAHVIPTASREAAYTYAIASAGAAYAVTAACARGNISTCGCD-VRHKATPTGGGTPDEP 142
            :....||..|:...:||||:.|||:|||.|:|||.||:.|.:..|||| ..|..:|.|
Human   114 LDSLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGELEKCGCDRTVHGVSPQG------- 171

  Fly   143 WKWGGCSADVDFGMRYARRFMDARELER---DSRTLMNLHNNRAGRTLVKKMLRTDCKCHGVSGS 204
            ::|.|||.::.:|:.:::.|:|.||..:   .||.|||||||.|||..:...:|.:|||||||||
Human   172 FQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGS 236

  Fly   205 CVMKTCWKSLPPFRLVGDRLMLKYQKAKTVQAVKGKRGLRLVLSRKKHAGTARAQ-------KPV 262
            |.:||||:::||||.||..|..|:..|..|:              .:..|::||.       ||.
Human   237 CEVKTCWRAVPPFRQVGHALKEKFDGATEVE--------------PRRVGSSRALVPRNAQFKPH 287

  Fly   263 LDWPKRMELIYLEASPNYCERSLQTGSQGTSGRTCQRTGHGPQSCDLLCCGRGHNTQHIRRTTQC 327
            .|    .:|:|||.||::||:.:::|..||.||||.:|......|:|||||||.:|..:....:|
Human   288 TD----EDLVYLEPSPDFCEQDMRSGVLGTRGRTCNKTSKAIDGCELLCCGRGFHTAQVELAERC 348

  Fly   328 RCQFRWCCEVKCDECDESYEEFTCK 352
            .|:|.|||.|||.:|....|..||:
Human   349 SCKFHWCCFVKCRQCQRLVELHTCR 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt2	NP_476810.1	wnt	36..352	CDD:278536	134/326 (41%)
WNT4	XP_011539899.1	wnt	71..373	CDD:278536	134/326 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152281
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326151at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40508
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X108
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.750