Protein Alignment Wnt2 and Wnt5

DIOPT Version :10

• Sequence 1: NP_476810.1
• Gene: Wnt2 / 35975
• FlyBaseID: FBgn0004360
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_476924.1
• Gene: Wnt5 / 32838
• FlyBaseID: FBgn0010194
• Length: 1004
• Species: Drosophila melanogaster
• Alignment Length: 481
• Identity: 129/481 - (26%)
• Similarity: 179/481 - (37%)
• Gaps: 182/481 - (37%)

  Fly    30 CGRIPGLTPGQRNMCREMPDALIALGEGHQLGAQECQHQFRGHRWNCSEVWQRNVFAHVIPTASR 94
            |....||:..|:..|.:....:.|:..|.:...||||.||:..|||||......||..:...|:.
  Fly   548 CYSAIGLSNSQKKQCVKHTSVMPAISRGARAAIQECQFQFKNRRWNCSTTNDETVFGPMTSLAAP 612

  Fly    95 EAAYTYAIASAGAAYAVTAACARGNISTCGCDVRHKATPTGGGTP---DEPWKWGGCSADVDFGM 156
            |.|:.:|:|:|.....:..||..|.:::|.|        :.|..|   .:.||||||..:::|..
  Fly   613 EMAFIHALAAATVTSFIARACRDGQLASCSC--------SRGSRPKQLHDDWKWGGCGDNLEFAY 669

  Fly   157 RYARRFMDARELERD-------------------------------------------------- 171
            ::|..|:|:||.|.:
  Fly   670 KFATDFIDSREKETNRETRGVKRKREEINKNRMHSDDTNAFNIGIKRNKNVDAKNDTSLVVRNVR 734

  Fly   172 ----------------------------------------------------------------- 171
                                                                             
  Fly   735 KSTEAENSHILNENFDQHLLELEQRITKEILTSKIDEEEMIKLQEKIKQEIVNTKFFKGEQQPRK 799

  Fly   172 --------------------------------------SRTLMNLHNNRAGRTLVKKMLRTDCKC 198
                                                  :|:|||||||.|||..|.|..|..|||
  Fly   800 KKRKNQRAAADAPAYPRNGIKESYKDGGILPRSTATVKARSLMNLHNNEAGRRAVIKKARITCKC 864

  Fly   199 HGVSGSCVMKTCWKSLPPFRLVGDRLMLKYQKAKTVQAVKGKRGLRLVLSRKKHAGTARAQKPVL 263
            |||||||.:.|||:.|...|.:||.|..||:.|..|:.  .|||              |.|...|
  Fly   865 HGVSGSCSLITCWQQLSSIREIGDYLREKYEGATKVKI--NKRG--------------RLQIKDL 913

  Fly   264 DW--PKRMELIYLEASPNYCERSLQTGSQGTSGRTCQRTGHGPQSCDLLCCGRGHNTQHIRRTTQ 326
            .:  |...:||||:.||::|..|......||.||.|.:...|.:||.:||||||:||::|....:
  Fly   914 QFKVPTAHDLIYLDESPDWCRNSYALHWPGTHGRVCHKNSSGLESCAILCCGRGYNTKNIIVNER 978

  Fly   327 CRCQFRWCCEVKCDECDESYEEFTCK 352
            |.|:|.|||:|||:.|.:..||.|||
  Fly   979 CNCKFHWCCQVKCEVCTKVLEEHTCK 1004

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt2	NP_476810.1	Wnt_Wnt7	29..352	CDD:381713	127/479 (27%)
Wnt5	NP_476924.1	Wnt_Wnt5	548..1004	CDD:381711	127/479 (27%)