Protein Alignment Wnt2 and Wnt8a

DIOPT Version :10

• Sequence 1: NP_476810.1
• Gene: Wnt2 / 35975
• FlyBaseID: FBgn0004360
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_001099625.1
• Gene: Wnt8a / 291678
• RGDID: 1306312
• Length: 359
• Species: Rattus norvegicus
• Alignment Length: 318
• Identity: 127/318 - (39%)
• Similarity: 172/318 - (54%)
• Gaps: 38/318 - (11%)

  Fly    50 ALIALGEGHQLGAQECQHQFRGHRWNCSEVWQRNVF---AHVIPT-ASREAAYTYAIASAGAAYA 110
            |.:|||.  |:|.:||:.||...||||.|    :.|   .|..|. |:||.::.:||.||...||
  Rat    45 ASVALGA--QMGMEECKFQFAWERWNCPE----HAFQFSTHTRPRGATRETSFIHAIRSAAVMYA 103

  Fly   111 VTAACARGNISTCGCDVRHKATPTGGGTPDEPWKWGGCSADVDFGMRYARRFMDARELERDSRTL 175
            ||..|:.|::.|||||..:.....|.|     |.|||||.:|:||.:.:|.|:|:.|..:|:|.|
  Rat   104 VTKNCSMGDLETCGCDESNNGKAGGHG-----WIWGGCSDNVEFGEKISRLFVDSLEKGKDARAL 163

  Fly   176 MNLHNNRAGRTLVKKMLRTDCKCHGVSGSCVMKTCWKSLPPFRLVGDRLMLKYQKAKTVQAVKGK 240
            ||||||||||..|:..::..|||||:||||.::|||..|..||.:|:.|..||.:|..::.  .|
  Rat   164 MNLHNNRAGRLAVRASMKRTCKCHGISGSCSIQTCWLQLADFRQMGNYLKAKYDRALKIET--DK 226

  Fly   241 RGLRLVLSRKKHAGTARAQ---KPVLDW--PKRMELIYLEASPNYCERSLQTGSQGTSGRTCQRT 300
            |.||        ||. ||:   .|:..:  ....|||:||.||:||.|:...|..||.||.|.:.
  Rat   227 RQLR--------AGN-RAEGRWAPIEAFLPSAEAELIFLEGSPDYCNRNASLGIYGTEGRECLQN 282

  Fly   301 GHG-----PQSCDLLC--CGRGHNTQHIRRTTQCRCQFRWCCEVKCDECDESYEEFTC 351
            ...     .:||..||  ||.....:.....:.|.|.|:|||.|||.:|......:.|
  Rat   283 ARSASRWEQRSCGRLCTECGLQVEERRTEAVSSCDCNFQWCCTVKCGQCRRVVNRYYC 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt2	NP_476810.1	Wnt_Wnt7	29..352	CDD:381713	127/318 (40%)
Wnt8a	NP_001099625.1	Wnt	35..341	CDD:393294	127/318 (40%)