Protein Alignment Wnt2 and Wnt5b

DIOPT Version :10

• Sequence 1: NP_476810.1
• Gene: Wnt2 / 35975
• FlyBaseID: FBgn0004360
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_001093959.1
• Gene: Wnt5b / 282582
• RGDID: 628850
• Length: 372
• Species: Rattus norvegicus
• Alignment Length: 377
• Identity: 152/377 - (40%)
• Similarity: 210/377 - (55%)
• Gaps: 54/377 - (14%)

  Fly     8 LLIYIL-----WIMEIRLVSSFTSVML----------------CGRIPGLTPGQRNMCREMPDAL 51
            ||:::.     |...:...:|:.|:.|                |.::|||:||||.:|:...:.:
  Rat    18 LLLFVAALLSSWAQLLTDANSWWSLALNPVQRPEMFIIGAQPVCSQLPGLSPGQRKLCQLYQEHM 82

  Fly    52 IALGEGHQLGAQECQHQFRGHRWNCSEVWQRNVFAHVIPTASREAAYTYAIASAGAAYAVTAACA 116
            ..:|||.:.|.:|||||||..|||||.|...:||..|:...|||.|:|||:::||...|::.||.
  Rat    83 SYIGEGAKTGIRECQHQFRQRRWNCSTVDNLSVFGRVMQIGSRETAFTYAVSAAGVVNAISRACR 147

  Fly   117 RGNISTCGCD--VRHKATPTGGGTPDEPWKWGGCSADVDFGMRYARRFMDARELERD-------- 171
            .|.:|||||.  .|.|..|       ..|.||||..:|::|.|:|:.|:||||.|::
  Rat   148 EGELSTCGCSRAARPKDLP-------RDWLWGGCGDNVEYGYRFAKEFVDAREREKNFAKGSEEQ 205

  Fly   172 SRTLMNLHNNRAGRTLVKKMLRTDCKCHGVSGSCVMKTCWKSLPPFRLVGDRLMLKYQKAKTVQA 236
            .|.||||.||.|||..|.||....||||||||||.:||||..|..||.|||||..||..|..::.
  Rat   206 GRALMNLQNNEAGRRAVYKMADVSCKCHGVSGSCSLKTCWLQLAEFRKVGDRLKEKYDSAAAMRI 270

  Fly   237 VK-GKRGLRLVLSRKKHAGTARAQKPVLDWPKRMELIYLEASPNYCERSLQTGSQGTSGRTCQRT 300
            .: ||  |.|..||             .:.|...:|:|::.||:||.|:..|||.||.||.|.:|
  Rat   271 TRQGK--LELTNSR-------------FNQPSPEDLVYVDPSPDYCLRNETTGSLGTQGRLCNKT 320

  Fly   301 GHGPQSCDLLCCGRGHNTQHIRRTTQCRCQFRWCCEVKCDECDESYEEFTCK 352
            ..|...|:|:|||||::.....:..:|.|:|.|||.|:|.:|.|..:::.||
  Rat   321 SEGTDGCELMCCGRGYDRFKSVQVERCHCRFHWCCFVRCKKCTEIVDQYVCK 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt2	NP_476810.1	Wnt_Wnt7	29..352	CDD:381713	145/349 (42%)
Wnt5b	NP_001093959.1	Wnt	61..372	CDD:393294	144/332 (43%)