Protein Alignment Wnt2 and Wnt7a

DIOPT Version :9

• Sequence 1: NP_476810.1
• Gene: Wnt2 / 35975
• FlyBaseID: FBgn0004360
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_033553.2
• Gene: Wnt7a / 22421
• MGIID: 98961
• Length: 349
• Species: Mus musculus
• Alignment Length: 352
• Identity: 172/352 - (48%)
• Similarity: 229/352 - (65%)
• Gaps: 22/352 - (6%)

  Fly     9 LIYILWIMEIRLVSSFTSV------MLCGRIPGLTPGQRNMCREMPDALIALGEGHQLGAQECQH 67
            |...|.|:.:| :..|:||      ::|.:||||.|.||.:|:..|||:|.:|||.|:|..|||.
Mouse    12 LFLSLGIVYLR-IGGFSSVVALGASIICNKIPGLAPRQRAICQSRPDAIIVIGEGSQMGLDECQF 75

  Fly    68 QFRGHRWNCSEVWQRNVFAHVIPTASREAAYTYAIASAGAAYAVTAACARGNISTCGCDVRHKAT 132
            |||..|||||.:.:|.||...:...|||||:||||.:||.|:|:||||.:||:|.||||...:
Mouse    76 QFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQ-- 138

  Fly   133 PTGGGTPDEPWKWGGCSADVDFGMRYARRFMDARELERDSRTLMNLHNNRAGRTLVKKMLRTDCK 197
              |....||.|||||||||:.:|:.:|:.|:||||:::::|||||||||.|||.::::.::.:||
Mouse   139 --GQYHRDEGWKWGGCSADIRYGIGFAKVFVDAREIKQNARTLMNLHNNEAGRKILEENMKLECK 201

  Fly   198 CHGVSGSCVMKTCWKSLPPFRLVGDRLMLKYQKAKTVQAVKGKRGLRLVLSRKKHAGTARAQKPV 262
            ||||||||..||||.:||.||.:|..|..||.:|..|:.|:.        ||.|.....:.:||
Mouse   202 CHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEPVRA--------SRNKRPTFLKIKKP- 257

  Fly   263 LDWPKRM--ELIYLEASPNYCERSLQTGSQGTSGRTCQRTGHGPQSCDLLCCGRGHNTQHIRRTT 325
            |.:.|.|  :|:|:|.||||||....|||.||.||.|.:|......|||:|||||:||....|..
Mouse   258 LSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVW 322

  Fly   326 QCRCQFRWCCEVKCDECDESYEEFTCK 352
            ||.|:|.|||.|||:.|.|..|.:|||
Mouse   323 QCNCKFHWCCYVKCNTCSERTEMYTCK 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt2	NP_476810.1	wnt	36..352	CDD:278536	159/317 (50%)
Wnt7a	NP_033553.2	Wnt_Wnt7a	32..349	CDD:381723	163/329 (50%)
		Disordered linker. /evidence=ECO:0000250|UniProtKB:O00755	238..266		10/36 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842329
Domainoid	1	1.000	353	1.000	Domainoid score	I999
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	358	1.000	Inparanoid score	I2208
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326151at33208
OrthoFinder	1	1.000	-	-		FOG0002358
OrthoInspector	1	1.000	-	-		otm42581
orthoMCL	1	0.900	-	-		OOG6_107270
Panther	1	1.100	-	-	O	PTHR12027
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X108
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.760