Protein Alignment Wnt2 and Wnt6

DIOPT Version :10

• Sequence 1: NP_476810.1
• Gene: Wnt2 / 35975
• FlyBaseID: FBgn0004360
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_033552.2
• Gene: Wnt6 / 22420
• MGIID: 98960
• Length: 364
• Species: Mus musculus
• Alignment Length: 371
• Identity: 148/371 - (39%)
• Similarity: 193/371 - (52%)
• Gaps: 45/371 - (12%)

  Fly     8 LLIYIL---------WIMEIRLVSSFTSVMLCGRIPGLTPGQRNMCREMPDALIALGEGHQLGAQ 63
            ||:.:|         |.:...||...||:  |.:...|...|..:|:..|:.:..|..|.:||.:
Mouse    11 LLLLLLCPAHVDGLWWAVGSPLVMDPTSI--CRKARRLAGRQAELCQAEPEVVAELARGARLGVR 73

  Fly    64 ECQHQFRGHRWNCSEVWQRNVFAHVIPTASREAAYTYAIASAGAAYAVTAACARGNISTCGCDV- 127
            |||.|||..|||||.  ....|..|:....||.|:.:||.:|||::|||.||:.|.:..|||..
Mouse    74 ECQFQFRFRRWNCSS--HSKAFGRVLQQDIRETAFVFAITAAGASHAVTQACSMGELLQCGCQAP 136

  Fly   128 RHKATPTGG---GTPDEP-----------WKWGGCSADVDFGMRYARRFMDAREL--ERDSRTLM 176
            |.:|.|...   |||..|           |:||||..|||||...:|.||||:..  ..|.|.|:
Mouse   137 RGRAPPRPSGLLGTPGPPGPTGSPDASAAWEWGGCGDDVDFGDEKSRLFMDAQHKRGRGDIRALV 201

  Fly   177 NLHNNRAGRTLVKKMLRTDCKCHGVSGSCVMKTCWKSLPPFRLVGDRLMLKYQKAKTVQAVK-GK 240
            .||||.|||..|:...||:|||||:||||.::|||:.|||||.||.||:.::..|..|.... ||
Mouse   202 QLHNNEAGRLAVRSHTRTECKCHGLSGSCALRTCWQKLPPFREVGARLLERFHGASRVMGTNDGK 266

  Fly   241 RGLRLVLSRKKHAGTARAQKPVLDWPKRMELIYLEASPNYCERSLQTGSQGTSGRTCQRTGHGPQ 305
            ..|..|          |..||    |.|.:|:|...||::|..:.:|||.||.||.|..:.....
Mouse   267 ALLPAV----------RTLKP----PGRADLLYAADSPDFCAPNRRTGSPGTRGRACNSSAPDLS 317

  Fly   306 SCDLLCCGRGHNTQHIRRTTQCRCQFRWCCEVKCDECDESYEEFTC 351
            .||||||||||..:.::....|.|:|.|||.|:|..|....|...|
Mouse   318 GCDLLCCGRGHRQESVQLEENCLCRFHWCCVVQCHRCRVRKELSLC 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt2	NP_476810.1	Wnt_Wnt7	29..352	CDD:381713	140/341 (41%)
Wnt6	NP_033552.2	Wnt_Wnt6	34..364	CDD:381712	142/348 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..162		6/21 (29%)