Protein Alignment Wnt2 and Wnt4

DIOPT Version :10

• Sequence 1: NP_476810.1
• Gene: Wnt2 / 35975
• FlyBaseID: FBgn0004360
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_033549.1
• Gene: Wnt4 / 22417
• MGIID: 98957
• Length: 351
• Species: Mus musculus
• Alignment Length: 366
• Identity: 142/366 - (38%)
• Similarity: 207/366 - (56%)
• Gaps: 45/366 - (12%)

  Fly     7 KLLIYI---------LWIMEIRLVSSFTSVMLCGRIPGLTPGQRNMCREMPDALIALGEGHQLGA 62
            :||::.         |::.::..|.|.:....|.::.||...|..||:...:.:.::..|.||..
Mouse    11 RLLVFAVFSAAASNWLYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRGAQLAI 75

  Fly    63 QECQHQFRGHRWNCSEVWQRNVFAHVIPTASREAAYTYAIASAGAAYAVTAACARGNISTCGCD- 126
            :|||:|||..|||||.:....||..|:...:||||:.|||:|||.|:|||.||:.|.:..||||
Mouse    76 EECQYQFRNRRWNCSTLDSLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGELEKCGCDR 140

  Fly   127 VRHKATPTGGGTPDEPWKWGGCSADVDFGMRYARRFMDARELER---DSRTLMNLHNNRAGRTLV 188
            ..|..:|.|       ::|.|||.::.:|:.:::.|:|.||..:   .||.|||||||.|||..:
Mouse   141 TVHGVSPQG-------FQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAI 198

  Fly   189 KKMLRTDCKCHGVSGSCVMKTCWKSLPPFRLVGDRLMLKYQKAKTVQAVKGKRGLRLVLSRKKHA 253
            ...:|.:||||||||||.:||||:::||||.||..|..|:..|..|:              .:..
Mouse   199 LTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVE--------------PRRV 249

  Fly   254 GTARAQ-------KPVLDWPKRMELIYLEASPNYCERSLQTGSQGTSGRTCQRTGHGPQSCDLLC 311
            |::||.       ||..|    .:|:|||.||::||:.:::|..||.||||.:|......|:|||
Mouse   250 GSSRALVPRNAQFKPHTD----EDLVYLEPSPDFCEQDIRSGVLGTRGRTCNKTSKAIDGCELLC 310

  Fly   312 CGRGHNTQHIRRTTQCRCQFRWCCEVKCDECDESYEEFTCK 352
            ||||.:|..:....:|.|:|.|||.|||.:|....|..||:
Mouse   311 CGRGFHTAQVELAERCGCRFHWCCFVKCRQCQRLVEMHTCR 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt2	NP_476810.1	Wnt_Wnt7	29..352	CDD:381713	136/333 (41%)
Wnt4	NP_033549.1	Wnt_Wnt4	43..351	CDD:381710	136/332 (41%)