DRSC/TRiP Functional Genomics Resources

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Protein Alignment Wnt2 and Wnt10a

DIOPT Version :9

Sequence 1:NP_476810.1 Gene:Wnt2 / 35975 FlyBaseID:FBgn0004360 Length:352 Species:Drosophila melanogaster
Sequence 2:NP_033544.1 Gene:Wnt10a / 22409 MGIID:108071 Length:417 Species:Mus musculus


Alignment Length:365 Identity:141/365 - (38%)
Similarity:188/365 - (51%) Gaps:48/365 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 LCGRIPGLTPGQRNMCREMPDALIALGEGHQLGAQECQHQFRGHRWNCSEVWQRNVFAHVIPTAS 93
            :|..:|||:..|..:|...||...:..:|.|:...|||||||..|||||.:..||...:..|..|
Mouse    60 VCLTLPGLSRRQMEVCVRHPDVAASAIQGIQIAIHECQHQFRDQRWNCSSLETRNKVPYESPIFS 124

  Fly    94 ---REAAYTYAIASAGAAYAVTAACARGNISTCGCDVRHK----------------ATPTG---- 135
               ||:|:.||||:||..:||:.|||.|.:..||||...:                |...|    
Mouse   125 RGFRESAFAYAIAAAGVVHAVSNACALGKLKACGCDASRRGDEEAFRRKLHRLQLDALQRGKGLS 189

  Fly   136 GGTPDEP------------WKWGGCSADVDFGMRYARRFMDARELERDSRTLMNLHNNRAGRTLV 188
            .|.|:.|            |:|||||.||.||.|:::.|:|:||..||....|.|||||.||..|
Mouse   190 HGVPEHPAILPASPGLQDSWEWGGCSPDVGFGERFSKDFLDSREPHRDIHARMRLHNNRVGRQAV 254

  Fly   189 KKMLRTDCKCHGVSGSCVMKTCWKSLPPFRLVGDRLMLKYQKAKTVQAVKGKRGLRLVLSRKKHA 253
            .:.:|..|||||.||||.:||||:..|.||.||..|..::.:|..::. ..:.|.:|      ..
Mouse   255 MENMRRKCKCHGTSGSCQLKTCWQVTPEFRTVGALLRNRFHRATLIRP-HNRNGGQL------EP 312

  Fly   254 GTARAQKPVLDWP------KRMELIYLEASPNYCERSLQTGSQGTSGRTCQRTGHGPQSCDLLCC 312
            |.|.|..|....|      ...:|:|.|.||::|||..:..|.||.||.|.::..||..|..:||
Mouse   313 GPAGAPSPAPGTPGLRRRASHSDLVYFEKSPDFCEREPRLDSAGTVGRLCNKSSTGPDGCGSMCC 377

  Fly   313 GRGHNTQHIRRTTQCRCQFRWCCEVKCDECDESYEEFTCK 352
            |||||.....|:.:|.|:|.|||.|.|:||..:.....||
Mouse   378 GRGHNILRQTRSERCHCRFHWCCFVVCEECRITEWVSVCK 417

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Wnt2NP_476810.1 wnt 36..352 CDD:278536 136/356 (38%)
Wnt10aNP_033544.1 wnt 67..417 CDD:278536 136/356 (38%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 300..327 7/33 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167842335
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3913
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.740

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