Protein Alignment Wnt2 and Wnt1

DIOPT Version :10

• Sequence 1: NP_476810.1
• Gene: Wnt2 / 35975
• FlyBaseID: FBgn0004360
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_067254.1
• Gene: Wnt1 / 22408
• MGIID: 98953
• Length: 370
• Species: Mus musculus
• Alignment Length: 313
• Identity: 133/313 - (42%)
• Similarity: 177/313 - (56%)
• Gaps: 22/313 - (7%)

  Fly    36 LTPGQRNMCREMPDALIALGEGHQLGAQECQHQFRGHRWNCSEVWQRNVFAHVIPTASREAAYTY 100
            |:..||.:.|:.|..|.::..|.|...:||:.|||..||||......::|..::....||.|:.:
Mouse    64 LSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPGPHLFGKIVNRGCRETAFIF 128

  Fly   101 AIASAGAAYAVTAACARGNISTCGCDVRHKATPTGGGTPDEPWKWGGCSADVDFGMRYARRFMDA 165
            ||.|||..::|..:|:.|:|.:|.||.|.:    |.|.||  |.|||||.::|||..:.|.|:|:
Mouse   129 AITSAGVTHSVARSCSEGSIESCTCDYRRR----GPGGPD--WHWGGCSDNIDFGRLFGREFVDS 187

  Fly   166 RELERDSRTLMNLHNNRAGRTLVKKMLRTDCKCHGVSGSCVMKTCWKSLPPFRLVGDRLMLKYQK 230
            .|..||.|.|||||||.||||.|...:|.:|||||:||||.::|||..||..|.|||.|..::..
Mouse   188 GEKGRDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDG 252

  Fly   231 AKTVQAVKGKRGLRLVLSRKKHAGTAR------AQKPVLDWPKRMELIYLEASPNYCERSLQTGS 289
            |..|  :.|.||    .:|...|...|      |.||    |...:|:|.|.|||:|..|.:.|:
Mouse   253 ASRV--LYGNRG----SNRASRAELLRLEPEDPAHKP----PSPHDLVYFEKSPNFCTYSGRLGT 307

  Fly   290 QGTSGRTCQRTGHGPQSCDLLCCGRGHNTQHIRRTTQCRCQFRWCCEVKCDEC 342
            .||:||.|..:......|:||||||||.|:..|.|.:|.|.|.|||.|.|..|
Mouse   308 AGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFHWCCHVSCRNC 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt2	NP_476810.1	Wnt_Wnt7	29..352	CDD:381713	133/313 (42%)
Wnt1	NP_067254.1	Wnt_Wnt1	64..370	CDD:381707	133/313 (42%)