Protein Alignment Wnt2 and Wnt2b

DIOPT Version :10

• Sequence 1: NP_476810.1
• Gene: Wnt2 / 35975
• FlyBaseID: FBgn0004360
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_001178777.1
• Gene: Wnt2b / 116466
• RGDID: 69346
• Length: 391
• Species: Rattus norvegicus
• Alignment Length: 358
• Identity: 149/358 - (41%)
• Similarity: 217/358 - (60%)
• Gaps: 34/358 - (9%)

  Fly     8 LLIYILWIMEIRLVSSFTSV------MLCGRIPGLTPGQRNMCREMPDALIALGEGHQLGAQECQ 66
            ||:.:|..:..|:.:|:..:      ::|..||||...||.:|:..||.:.::|||.:...:|||
  Rat    44 LLLLLLLTLPARVDTSWWYIGALGARVICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQ 108

  Fly    67 HQFRGHRWNCSEV-WQRNVFAHVIPTASREAAYTYAIASAGAAYAVTAACARGNISTCGCDVRHK 130
            ||||.|||||:.: ....||...:..:|||||:.|||:|||..:|:|.||::|.:|.|.||
  Rat   109 HQFRHHRWNCTTLDRDHTVFGRAMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCD---- 169

  Fly   131 ATP-TGGGTPDE--PWKWGGCSADVDFGMRYARRFMDARELE-RDSRTLMNLHNNRAGRTLVKKM 191
              | |.|...|:  .:.|||||.::.:|:|:|:.|:||:|.. :|:|.||||||||.|||.|::.
  Rat   170 --PYTRGRHHDQRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRLKDARALMNLHNNRCGRTAVRRF 232

  Fly   192 LRTDCKCHGVSGSCVMKTCWKSLPPFRLVGDRLMLKYQKAKTVQAVKGKRGLRLVLSRK--KHAG 254
            |:.:||||||||||.::|||::|..||..||.|..:|..|  ||....:.|.....:|:  :||
  Rat   233 LKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGA--VQVTATQDGANFTAARQGYRHA- 294

  Fly   255 TARAQKPVLDWPKRMELIYLEASPNYCERSLQTGSQGTSGRTCQRTGHGPQSCDLLCCGRGHNTQ 319
                        .|.:|:|.:.||:||......||.||:||.|.:|..|...|:::|||||::|.
  Rat   295 ------------TRTDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTT 347

  Fly   320 HIRRTTQCRCQFRWCCEVKCDECDESYEEFTCK 352
            .:.|.|||.|:|.|||.|:|.||..:.:..|||
  Rat   348 RVTRVTQCECKFHWCCAVRCKECRNTVDVHTCK 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt2	NP_476810.1	Wnt_Wnt7	29..352	CDD:381713	142/329 (43%)
Wnt2b	NP_001178777.1	Wnt_Wnt2b	67..380	CDD:381720	142/333 (43%)