DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wnt2 and wnt2

DIOPT Version :9

Sequence 1:	NP_476810.1	Gene:	Wnt2 / 35975	FlyBaseID:	FBgn0004360	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	XP_012815404.1	Gene:	wnt2 / 100038261	XenbaseID:	XB-GENE-486595	Length:	365	Species:	Xenopus tropicalis

Alignment Length:	365	Identity:	146/365 - (40%)
Similarity:	222/365 - (60%)	Gaps:	33/365 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWKIHNKLLIYIL-------WIMEIRLVSSFTSVMLCGRIPGLTPGQRNMCREMPDALIALGEGH 58
            :|.:....|:::.       |.|...:.||.:|.::|..||||...||.:|:..|:.:..:|.|.
Frog     8 IWFLVPTTLLFLTPEAANSWWYMGAVVTSSSSSRVMCNNIPGLVTRQRQLCQRYPEIMQVIGLGA 72

  Fly    59 QLGAQECQHQFRGHRWNCSEVWQR--NVFAHVIPTASREAAYTYAIASAGAAYAVTAACARGNIS 121
            .....|||||||.|||||: :.:|  ::|..:|..:|||:|:.:||:|||..:|:|.||::|.:.
Frog    73 VEWTTECQHQFRHHRWNCN-IMERDQSLFGKLILRSSRESAFVHAISSAGIVFAITRACSQGELK 136

  Fly   122 TCGCDVRHKATPTGGGTPDEP---WKWGGCSADVDFGMRYARRFMDARELE-RDSRTLMNLHNNR 182
            :|.||      ||..|:..:.   :.|.|||.::|:|:|:||.|:||:|.: :|:|.|||||||:
Frog   137 SCSCD------PTKKGSSKDSKGGFDWDGCSDNIDYGIRFARTFVDAKERKGKDARALMNLHNNK 195

  Fly   183 AGRTLVKKMLRTDCKCHGVSGSCVMKTCWKSLPPFRLVGDRLMLKYQKAKTVQAVKGKRGLRLVL 247
            |||..||:.::.:||||||||||.::|||.::..||..||.|..||..|  :|.|..:.|....:
Frog   196 AGRKAVKRFMKQECKCHGVSGSCTVRTCWMAMGDFRKSGDYLRRKYNGA--IQVVMNQDGTGFTV 258

  Fly   248 SRKKHAGTARAQKPVLDWPKRMELIYLEASPNYCERSLQTGSQGTSGRTCQRTGHGPQSCDLLCC 312
            :      ..|.:||.     ..:|:|.|.||:||.|....||.||:||.|.:|..|..||:::||
Frog   259 A------NTRFKKPT-----NNDLVYFENSPDYCVRDRDVGSLGTAGRICNQTSRGMDSCEVMCC 312

  Fly   313 GRGHNTQHIRRTTQCRCQFRWCCEVKCDECDESYEEFTCK 352
            |||::|..|.:.::|.|:|.|||.|:|.:|.|:.:..|||
Frog   313 GRGYDTARITKMSKCECKFHWCCSVRCKDCIETVDIHTCK 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wnt2	NP_476810.1	wnt	36..352	CDD:278536	133/321 (41%)
wnt2	XP_012815404.1	Wnt_Wnt2	41..352	CDD:381719	137/330 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326151at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X108
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920