DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Camta and SPAC26H5.05

DIOPT Version :9

Sequence 1:	NP_001137624.1	Gene:	Camta / 35974	FlyBaseID:	FBgn0287478	Length:	2044	Species:	Drosophila melanogaster
Sequence 2:	NP_594452.1	Gene:	SPAC26H5.05 / 2542701	PomBaseID:	SPAC26H5.05	Length:	1151	Species:	Schizosaccharomyces pombe

Alignment Length:	977	Identity:	189/977 - (19%)
Similarity:	341/977 - (34%)	Gaps:	275/977 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   759 QQQQQQQQHQQQQQHLSLQRFVASQGQNSVHLNQ------QHRLQ----IANTTITATASDP--- 810
            |.:.:.....:||.:::          .|:|||:      ||.:.    :|||.......:|
pombe    98 QDEAECLPSDRQQDYIN----------PSLHLNRTVFPTPQHSISDANFLANTVDQPLGDNPMFG 152

  Fly   811 -------------ATTLAAAAAVAAASGA--TPV----ALNIMDTELIENQNHMT--ANKITNSG 854
                         .....|......:|||  .|:    .:.:::|...|:.|.:|  |.....|.
pombe   153 ESDVYLLKMDPMKQAPYEAGFNSVKSSGAIEDPLQFRQPITMLETPFNESINTLTPYAEDYAFSS 217

  Fly   855 SSNSSSSNASKQLAGQTNNKLNVVNNNDPGNNNFMYNQQQQLNASSNSNNSSQQQQQQQQQHYYK 919
            .:.|:...::|:.|...|: |..:|.: ...:....|...:|...||.|.|...:       |.:
pombe   218 LNTSAPPLSNKEYAFSVNH-LPAINEH-KWKSRVETNMLFELRIKSNDNQSVPFE-------YLR 273

  Fly   920 L--------QQTTATPTSGQPPP--LAQVQPHSLAQPPVEAM------CMSPEHRSSSQPTPATS 968
            |        ::.::.|...||.|  :..:.|..||......:      |:..|.:.::: :.||.
pombe   274 LPSWAHREDKKRSSKPQPLQPDPETVIHLVPTVLAGDKSSVVKTCCTRCLLRERKRNAR-SQATK 337

  Fly   969 SAGSIPSSVSVSI---SVSTSTPT-------------PAPTSISTPTSGTSSTSSSLQSI-IDGN 1016
            .| .:|:...:..   :::.::|.             |....|.........|......: :|||
pombe   338 DA-CMPNYTKLKAYERNMTDASPEEKQQFRIKLLNQFPKLEDIDEDRMIMVFTGPEYVRLQLDGN 401

  Fly  1017 QQ-----QQITTTSTAATC----------------DNLMSANALSEQDSH----------TVNNQ 1050
            ::     .:||..|:..:|                |.|:....::..|.|          |..:.
pombe   402 ERVAHINARITCYSSHQSCPYFHIIWDLYSMSRLVDRLVFPEPVTVLDDHKSRNLTKSEKTGKSN 466

  Fly  1051 ATEAPNRSQLQSQSQSLSLNQNGCATYS-----------ASSDNSSQISDESSSFGGNNQNSSNS 1104
            :.:||:...| |:|.::.....|..|.|           :||:||..:..:.|:   ::.:|.||
pombe   467 SQQAPSNHVL-SKSNTVPNLVTGFPTRSDNPPNEKRRRTSSSENSRALDIQLSA---SDSHSPNS 527

  Fly  1105 STSEEEPQVEALSFFNETLDLSQEDIQRTLIANMPYNTTAAGATAPSTT------ITTGNTKLEL 1163
            .::.:..:..|.|.......||.              ||.:| .:||.:      :...:.....
pombe   528 KSTLKSVEGSAFSMSKSPSVLSM--------------TTPSG-VSPSISKNGFHVVRVPSDAAGF 577

  Fly  1164 SQQETKEKPAMGTETATE--------IEDDETDDVFANLDAFDMLVEFPELDLDDKQALNNTALE 1220
            .|::.:|:..:...|...        ..||.:..|.......::|.:|.|:...|   ..:|.::
pombe   578 QQRQQQEEGVLEAHTNESAPIAPFPYCTDDFSFSVEEKSSVNNLLTQFDEVAKPD---FVSTPIK 639

  Fly  1221 Q---SSFLGESAP--SQPRKVHNICDFSPEWSYTEGGVKVLVAGPWTSSNGGAYTVLFDAQPVP- 1279
            :   |||:..:.|  |....:..|.   |......||.:|.:.|. ...||  ...||...|..
pombe   640 ENVDSSFINMTPPDVSHAPLISRII---PNKGSIMGGYEVTILGA-NFFNG--LVCLFGDNPAAV 698

  Fly  1280 TQLVQEGVLRCYC-PAHEAGFVTLQVACGGFLVSNS--VMFEYKLSLLADAPFDATSSNDCLYKF 1341
            |....|..:...| ||..||  |:.|....:..|:.  |||.|:.:|          .|: |||.
pombe   699 TFSWSESTIIATCPPATNAG--TVPVTFQNYNSSSEAPVMFTYEDNL----------DNE-LYKL 750

  Fly  1342 TLLNRLSTIDEKLQVKTEHELT---------TDNTALYL------EPNFE--------------- 1376
            |    :..:..||....::.||         .|:.|.|:      .||.|
pombe   751 T----VQVLGLKLTGSIQNPLTLSKKLLSSWRDDFAQYITNSIKQPPNSESKGQSKKTLLHDSNM 811

  Fly  1377 EKLVAYCHKLIKHAWSMPSTAASWT---------------------VGLRGMTLLHLAAALGYAK 1420
            |.|.:...:::|...:....:...|                     |...|.:||||.||.|.:.
pombe   812 ESLKSVISRIVKKDSNQSDDSVESTILAAFALVTDTTTPYLSDFSLVNESGRSLLHLTAACGLSN 876

  Fly  1421 LVGAMLNWRSENPHIILETELDALSQDVYGFTPLAWACVRGHVE-CSLLLYKWNHNALK--IKTQ 1482
            ....:.|           ...|...:|..|:|||.:|.:..|.: |..||    .|..|  :...
pombe   877 ASTFLCN-----------AGCDVNKRDALGYTPLHYASLYDHKDICVNLL----SNGAKPDVIGA 926

  Fly  1483 AQQTPLDLASMRGHKVLLAQMYRLEKERCRKPQLRGGLANLSMNMGVEA-----EAEE---QHQS 1539
            :.:.|:||:|....|::..:....:.:...:..::....:::.|..:|:     |.||   |.:|
pombe   927 SGKKPIDLSSSEPIKLVFKEANNEQAQSISRSLIKDSEGSINTNETLESTSIVNEIEESAVQTKS 991

  Fly  1540 FS 1541
            :|
pombe   992 YS 993

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Camta	NP_001137624.1	CG-1	422..538	CDD:198144
		TIG	1242..1319	CDD:280079	23/80 (29%)
		ANK	<1405..1497	CDD:238125	26/94 (28%)
		ANK repeat	1405..1447	CDD:293786	10/41 (24%)
		Ank_2	1410..1500	CDD:289560	25/92 (27%)
		ANK repeat	1449..1481	CDD:293786	11/34 (32%)
SPAC26H5.05	NP_594452.1	IPT	658..741	CDD:238050	25/90 (28%)
		ANK	<853..938	CDD:238125	27/99 (27%)
		ANK repeat	861..892	CDD:293786	10/41 (24%)
		Ank_4	862..911	CDD:290365	17/59 (29%)
		ANK repeat	894..923	CDD:293786	11/32 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23335
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100