DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Camta and cutl-18

DIOPT Version :9

Sequence 1:	NP_001137624.1	Gene:	Camta / 35974	FlyBaseID:	FBgn0287478	Length:	2044	Species:	Drosophila melanogaster
Sequence 2:	NP_505875.2	Gene:	cutl-18 / 179565	WormBaseID:	WBGene00009830	Length:	801	Species:	Caenorhabditis elegans

Alignment Length:	502	Identity:	104/502 - (20%)
Similarity:	181/502 - (36%)	Gaps:	121/502 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 SGGNIIL---LRGTRNENGQIIIQNKQDILSLLSEQQQQQQQEKSHSSTAITLNQLPTAT----- 145
            |.|:.||   |.|.:|||||:|   .:|:     |..|..|...:|          ||.:
Worm   334 SDGSAILFDELGGCKNENGQLI---SKDL-----ELHQCMQLCATH----------PTRSCESIS 380

  Fly   146 -TVARKTIVQGSSGAGSSSSSSSSTISIVANSNNKEASSNTILLQTPINASQLESVLKAQERSKQ 209
             |.:|...:...:....:.:::.|..::...:..:|....||   .| ..|:::...||:..|..
Worm   381 YTKSRDCYLHDGAVETDNENTNCSVFTLNVITFEQELKPTTI---AP-GDSKVKKPHKAKTFSTG 441

  Fly   210 ANATQTKMVERPFMLKHATRSLSSESNCDSKSPFVLQTLKRLEKSQSILVIRNSTASTAATNTSM 274
            ....|.|:.||...:|.:::..||.                       |.::.||..|... .|:
Worm   442 NKKDQKKVEERKLYVKKSSKLGSSP-----------------------LDVKISTQCTFGF-ISV 482

  Fly   275 ATSP--PNGNSLATSSILSVTRTTKAAK--GVAG-ALHKLKAAAATTATSGGASSAGATSSTATT 334
            ..||  |:.::|....|......:..:|  |..| |:.|::....|..|..|  ....|....|.
Worm   483 KVSPGNPDNHNLVGGEIYVRNGHSNCSKTIGTDGEAILKIRHNDTTCITKNG--DIYETVVVVTQ 545

  Fly   335 ILRLGKSATTVAING-ASKLEATTST-TTAVPVPAT----ATTSNKLS-----NAVTSEQQQQQQ 388
            .:....:||.:.|:. ..|:....|. ..||.|..|    .|..|||.     |......:.:.:
Worm   546 NVESVGNATVITIDDQLFKVRCDYSNQKNAVAVAKTMNLRTTQFNKLDIYGKVNVKPMSMELRGK 610

  Fly   389 QQSTTTQTNVPLGNDGEPIKLPDNLESLPRADSFPSQRH-------RWNTNEEIAAILISFDKHG 446
            ::....:|          :||..:|:.:...|:..|.||       .::.|.:...|||   |:|
Worm   611 REIIKART----------VKLGQSLDLVFTVDNSTSARHVFVKKCTAYDQNGDEKIILI---KNG 662

  Fly   447 -------EWQSKEVRTRPKSGSLLLYSRKKVRYRRD---------GYCWKKRKDGKTTR------ 489
                   |:..::......:|.:|.:  :..|:::.         .||.|.:|....:|
Worm   663 CATQHAKEYVLRDEIKETATGFVLPF--RAFRFKQGEAVKIECEVKYCEKCKKANCPSRNRRFTT 725

  Fly   490 ----EDHMKLKVQGTECIYGCYVHSAILPTFHRRCYWLLQNPDIVLV 532
                ||......:.||.::...:...|:.:.....|.|..|..|.|:
Worm   726 FDESEDTTLTGNEDTEKVHAELLVQTIVDSTQLDGYCLQLNRWIALI 772

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Camta	NP_001137624.1	CG-1	422..538	CDD:198144	28/144 (19%)
		TIG	1242..1319	CDD:280079
		ANK	<1405..1497	CDD:238125
		ANK repeat	1405..1447	CDD:293786
		Ank_2	1410..1500	CDD:289560
		ANK repeat	1449..1481	CDD:293786
cutl-18	NP_505875.2	PAN_AP_HGF	105..177	CDD:238532
		PAN_AP	187..258	CDD:214680
		ZP	474..719	CDD:214579	53/262 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0520
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900