DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Camta and LOC100334756

DIOPT Version :9

Sequence 1:	NP_001137624.1	Gene:	Camta / 35974	FlyBaseID:	FBgn0287478	Length:	2044	Species:	Drosophila melanogaster
Sequence 2:	XP_021326543.1	Gene:	LOC100334756 / 100334756	-ID:	-	Length:	520	Species:	Danio rerio

Alignment Length:	626	Identity:	188/626 - (30%)
Similarity:	274/626 - (43%)	Gaps:	166/626 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1405 RGMTLLHLAAALGYAKLVGAMLNWRSENPHII-LETELDALSQDVYGFTPLAWACVRGHVECSLL 1468
            |||||||||||.||.:|:..::.|||.:.:.: ||.|:|.|:.|.:..|||.|||..||...::|
Zfish    23 RGMTLLHLAAAQGYTQLIHTLIRWRSISVNSLDLEQEVDPLNVDHFSCTPLMWACALGHQAAAVL 87

  Fly  1469 LYKWNHNALKIKTQAQQTPLDLASMRGHKVLLAQMYRLEKERCRKPQLRGGLANLSMNMGVEAEA 1533
            ||:|:..||.|.....:.||.:|..|||..|         .||                     .
Zfish    88 LYRWSSAALGIPDSLGRLPLAVAYSRGHTRL---------ARC---------------------L 122

  Fly  1534 EEQHQSFSAFDLELQRKHDGVFLRPVAVHSNQSPPNGSSRYSKRSSIDSGINMDIRSKSGKPLAR 1598
            ||.|                       .||.......|..|...|.:.|..:..:.|.|..|...
Zfish   123 EELH-----------------------THSQTQEHTASPPYRPPSPLSSSPDTGLSSSSSVPSPS 164

  Fly  1599 LHSNFESHDSYALG-VDSPLDSLTGTNCLLS---PLRKMD--FAL-CEVSTGESSPVHDKDCDDN 1656
            ...:.....:|:.| |..|:||.:..:...|   |:...|  |.: |:.::.....|...|....
Zfish   165 DPPSPSPSSAYSSGSVPDPMDSASSPSSPFSVPPPVGSTDSLFLMDCDAASPTEPHVPHADALSL 229

  Fly  1657 STSATDVTIG------NDLVLPDAVVGDSDAKVLTLAEHIIAAMPERIK-----NEADEMMVLGS 1710
            .:...|..:.      |:..|.|.|:   ...:.||||.||.|.|||||     .||:      |
Zfish   230 HSELADQLLNYSENAENEDYLSDEVL---QVDMATLAEQIIEATPERIKQEEFNREAE------S 285

  Fly  1711 PLTEPLTSESSALTDS--FMDPLLDSLPNTHFDSDFSFDFHDHSYRYHDVSTPCSSLSPASSGPL 1773
            ||.|  ..::.|:.|:  ::...||::              |.|.    ..||.|.||..:...|
Zfish   286 PLRE--RRDNPAIHDTMPWLATYLDTV--------------DRSL----CPTPPSLLSDLALQRL 330

  Fly  1774 QSPASYSILGTDPSVSSPSPPPSTKQLTEFLHASSISSYPFEADFSKLTLTDTEQRELYEAAKCI 1838
            :                   |||:....|||:||  ::...|.||:.|||||:|||||||||:.|
Zfish   331 R-------------------PPSSAAWAEFLNAS--ANGRMERDFALLTLTDSEQRELYEAARVI 374

  Fly  1839 QKAYRSYKGRQKLEEQNKERSAATVIQNYYRRYKQ-------YAYYRQMTNAALVIQHGYRSYRR 1896
            |.|:|.||||:..|:|:   .||.|||..||:|||       ||.|::||.||::||..:|||..
Zfish   375 QNAFRRYKGRRLKEQQD---MAAAVIQRCYRKYKQLTWIALKYALYKKMTQAAILIQSKFRSYYE 436

  Fly  1897 NKRFKKSGLCLSSSSDHGSVSSNSQCLSSFYDHYKQDQQQLHELGSQPSTPKETSPSGP------ 1955
            .|:|::|             ...:..:..:|..||:.::            .:..|.||
Zfish   437 QKKFQQS-------------RRAAVLIQQYYRSYKEYER------------VKQGPRGPGALNTK 476

  Fly  1956 LKRTYSQSTQNQAARKIQQFMRQSRIKLQKERAEKEKLVHQ 1996
            :|.::....|:||||||.:|:|:.|.:: ||..:.::|.|:
Zfish   477 IKGSFLTKKQDQAARKIMRFLRRCRHRI-KELKQSKELEHR 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Camta	NP_001137624.1	CG-1	422..538	CDD:198144
		TIG	1242..1319	CDD:280079
		ANK	<1405..1497	CDD:238125	43/92 (47%)
		ANK repeat	1405..1447	CDD:293786	22/42 (52%)
		Ank_2	1410..1500	CDD:289560	39/90 (43%)
		ANK repeat	1449..1481	CDD:293786	15/31 (48%)
LOC100334756	XP_021326543.1	ANK repeat	23..66	CDD:293786	22/42 (52%)
		ANK	24..>122	CDD:238125	46/127 (36%)
		ANK repeat	68..100	CDD:293786	15/31 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D161424at33208
OrthoFinder	1	1.000	-	-		FOG0001351
OrthoInspector	1	1.000	-	-		otm25244
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920