Protein Alignment ced-6 and CG8312

DIOPT Version :10

• Sequence 1: NP_001246225.1
• Gene: ced-6 / 35971
• FlyBaseID: FBgn0029092
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_649918.1
• Gene: CG8312 / 41163
• FlyBaseID: FBgn0037720
• Length: 866
• Species: Drosophila melanogaster
• Alignment Length: 690
• Identity: 122/690 - (17%)
• Similarity: 205/690 - (29%)
• Gaps: 248/690 - (35%)

  Fly    11 TAPTTTMPYQPANSGGTSGGSK--AAAKMAQLKFWNKQNSSK--QQQQDKDKDAADGGN-NTSGG 70
            |..||..|..|...|......|  .:..:|:| ..|..|:.|  :|:|.:....::||. ||..|
  Fly   105 TPATTAAPLPPVPIGTPPRQHKFVKSNSLARL-LGNTYNAKKFEKQEQKRLASGSEGGKFNTYSG 168

  Fly    71 GTG------------SNSNGDAKSEAKN-------------------------GKRNWLHTPEQL 98
            ..|            |..:||...|...                         |:.......:||
  Fly   169 RRGRAGPYLERFKRVSKEDGDVAGEDDTVRVTNVITLTTDSRDLLYGSRQEHVGRTGGYDQNDQL 233

  Fly    99 IS----------------GHAV--------YLVKFFGNLSVDQPK-GIEVVKEAIRKL--QFAQQ 136
            .|                .|:|        :.|.:.||:.....| |...|::.:..|  .:.|.
  Fly   234 TSKAYRTLTRSLGKLWRRTHSVDISTPDPEFKVSYLGNVLTGWAKAGEGCVEKQLNTLWRNYTQH 298

  Fly   137 MKKAETGTQEKFKKLEITIS-IKGVAIQEPRTHKILHQFPLYNISYCADEKGVKKFFSFIAKTVK 200
            .|      .:...:|::..| :|....|...|....|:     |:||...|...:.|.:|.:
  Fly   299 SK------PDVIMRLKVCASGLKATTRQHGLTEYWAHR-----ITYCCAPKNYPRVFCWIYR--- 349

  Fly   201 TQDGSDPTSNGHANGNGDGSAKVEESHECFVFI--SNKLASDITLTIGQAFDLAYRKYMDSTEKT 263
             .:|                .|::....|...:  ..|:|.||..|:.:..:.|.|::
  Fly   350 -HEG----------------RKLKHELRCHAVLCSKEKIAQDICDTLRENLESALREF------- 390

  Fly   264 NLSKAQQQINHLQQTVNVYKERLREVSAKLPKAELDALLFNLGIKDILEAPTTEPQNGIEVASEA 328
            ...|..:|...|.....||.      :..||:.::...:.....:..||...:.|:  :....||
  Fly   391 KREKILKQNARLSLANAVYD------NPSLPRRKIMLSVGGNNYRPPLERSKSAPK--LMAIEEA 447

  Fly   329 LSNGKLDDDKLLIDTNS------------------------------TTASTHSASP--SSFLPI 361
            :...:.|:   :.|||.                              .|....|.||  ||.:..
  Fly   448 IGEEEGDE---IEDTNEPEMMPCCQKDSLYPAMTLGRRRCRRGHSIRRTGKIQSFSPCCSSHMAK 509

  Fly   362 VPPRNNLSSQISIGGKSNS----------QKMDELLLNS-------------------------- 390
            ..|:....:..:.|..:|.          .|.|..|.|.
  Fly   510 ELPQEETKTMAAAGSSANDGSDSDDFEKLLKFDTTLSNELLPYFDMQLHKNSSQSMVSLSELKEE 574

  Fly   391 -----------DSDSDFDPRAD---ETQEIGGTGRSAISNMFGFEPANSFGQHLFSNNND----- 436
                       :||...||.||   |..::....||.:.         |.|:..|.::.|
  Fly   575 EGEPLSLLPTINSDPSADPEADYNAEDHDVTAPRRSGVC---------SDGEEDFLDDADDHYFR 630

  Fly   437 ---------------------------HKLQNNNSSLLITSNNNSINSS--GFSSELNITPPLLA 472
                                       |:.|::.||...:|...|.:::  |.|::..:|.|...
  Fly   631 HAAMLTMLHRSSMRKMRAADQTSLKYRHQTQSSISSNASSSTTASTSAAAGGGSAQQGLTSPDSD 695

  Fly   473 PPPKIAAPRRLNSVTTGNGLNGNTDLFGSDPFELNNGPNI 512
            .....:.....::||..|....|:... |||.:|...|::
  Fly   696 EGSISSGCETASTVTNANHEEYNSKRV-SDPGQLEQSPDL 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ced-6	NP_001246225.1	PTB_CED-6	92..261	CDD:269971	36/198 (18%)
CG8312	NP_649918.1	PID_2	263..442	CDD:405418	41/224 (18%)