Protein Alignment Pdk and Pdk4

DIOPT Version :10

• Sequence 1: NP_001097240.1
• Gene: Pdk / 35970
• FlyBaseID: FBgn0017558
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_038771.1
• Gene: Pdk4 / 27273
• MGIID: 1351481
• Length: 412
• Species: Mus musculus
• Alignment Length: 396
• Identity: 216/396 - (54%)
• Similarity: 283/396 - (71%)
• Gaps: 18/396 - (4%)

  Fly     9 SAASSSMASLA-KMLDFYSGFNPSPLSIKQFMDFG-QNACEKKSYIFLRKELPVRLANIMKEIAL 71
            ||:|.|.|||. :.::.:|.::|||||:||.:||| :||||:.|:.|||:|||||||||:|||.:
Mouse    10 SASSLSSASLVPREVELFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDI 74

  Fly    72 LPDNLLHTRSVSEVSSWYVKSFEDVL-VYEKAEPTHDNLQKFVADLDLIRNRHNDVVQTMAQGVI 135
            |||.|::|.||..|.|||::|..|:: .:||:......|.:||..|..:||||::||.|||||::
Mouse    75 LPDRLVNTPSVQLVKSWYIQSLMDLVEFHEKSPEDQKALSEFVDTLVKVRNRHHNVVPTMAQGIL 139

  Fly   136 EMKENEGGQVDAPTESSIQYFLDRLYMSRISIRMLINQHTLLFG----GNPHAGGRHIGCLDPAC 196
            |.|:.  ..||..|..::||||||.||:|||.|||:|||.|:|.    |||    .|||.:||.|
Mouse   140 EYKDT--CTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSKTGNP----SHIGSIDPNC 198

  Fly   197 DLSDVVRDAYENARFLCDQYYLTSPALEIQQHSSE-PGDNLPIRTVYVPSHLYYMLFELFKNSMR 260
            |:..||:||:|.|:.||||||||||.|.:.|.:.: ||.  ||..|||||||::||||||||:||
Mouse   199 DVVAVVQDAFECAKMLCDQYYLTSPELNLTQVNGKFPGQ--PIHIVYVPSHLHHMLFELFKNAMR 261

  Fly   261 AVVEHHGHDNNDTLPPLKVAICKGKEDICVKISDQGGGIPRSQTDQLFKYMYSTAPQPSKSDLHT 325
            |.|||  .:|..:|.|::..:..||||:.:||||:|||:|...||:||.|.|||||.|...:...
Mouse   262 ATVEH--QENRPSLTPVEATVVLGKEDLTIKISDRGGGVPLRITDRLFSYTYSTAPTPVMDNSRN 324

  Fly   326 VPLAGYGYGLPISRLYARYFHGDIVLLSCEGFGTDAIIYLKALSDEANELLPIFNKTSSKFYRAT 390
            .||||:|||||||||||:||.||:.|.|..|:||||||||||||.|:.|.||:|||::.|.|:.:
Mouse   325 APLAGFGYGLPISRLYAKYFQGDLNLYSMSGYGTDAIIYLKALSSESVEKLPVFNKSAFKHYQMS 389

  Fly   391 VPTGDW 396
            ....||
Mouse   390 SEADDW 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdk	NP_001097240.1	BCDHK_Adom3	32..193	CDD:463093	88/166 (53%)
		HATPase_PDK-like	197..366	CDD:340406	99/169 (59%)
Pdk4	NP_038771.1	BCDHK_Adom3	34..195	CDD:463093	88/166 (53%)
		HATPase_PDK-like	199..365	CDD:340406	99/169 (59%)