Protein Alignment Pdk and Pdk2

DIOPT Version :10

• Sequence 1: NP_001097240.1
• Gene: Pdk / 35970
• FlyBaseID: FBgn0017558
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_598428.2
• Gene: Pdk2 / 18604
• MGIID: 1343087
• Length: 407
• Species: Mus musculus
• Alignment Length: 401
• Identity: 227/401 - (56%)
• Similarity: 293/401 - (73%)
• Gaps: 11/401 - (2%)

  Fly     6 VRFSAASSSMASLAKMLDFYSGFNPSPLSIKQFMDFG-QNACEKKSYIFLRKELPVRLANIMKEI 69
            ||....::|:|...|.::.:|.|:|||||:|||:||| .|||||.|:.|||:|||||||||||||
Mouse     4 VRALLKNASLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEI 68

  Fly    70 ALLPDNLLHTRSVSEVSSWYVKSFEDVLVYEKAEP-THDNLQKFVADLDLIRNRHNDVVQTMAQG 133
            .||||.:|.|.||..|.||||:|..|::.:...:| .|..|.:|...|..|||||||||.|||||
Mouse    69 NLLPDRVLGTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQG 133

  Fly   134 VIEMKENEGGQVDAPTESSIQYFLDRLYMSRISIRMLINQHTLLFGG--NPHAGGRHIGCLDPAC 196
            |:|.|:..|.  |..:..:|||||||.|:||||||||||||||:|.|  || |..:|||.:||.|
Mouse   134 VLEYKDTYGD--DPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNP-AHPKHIGSIDPNC 195

  Fly   197 DLSDVVRDAYENARFLCDQYYLTSPALEIQQHSSEPGDNLPIRTVYVPSHLYYMLFELFKNSMRA 261
            .:||||:|||:.|:.|||:||:.||.||||:.:: ...|.||..||||||||:||||||||:|||
Mouse   196 SVSDVVKDAYDMAKLLCDKYYMASPDLEIQEVNA-TNANQPIHMVYVPSHLYHMLFELFKNAMRA 259

  Fly   262 VVEHHGHDNNDTLPPLKVAICKGKEDICVKISDQGGGIPRSQTDQLFKYMYSTAPQPSKSDLHTV 326
            .||  .|:::.||||:|:.:..|:||:.:|:||:|||:|..:.::||.|||||||.|......|
Mouse   260 TVE--SHESSLTLPPIKIMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQPGTGGT- 321

  Fly   327 PLAGYGYGLPISRLYARYFHGDIVLLSCEGFGTDAIIYLKALSDEANELLPIFNKTSSKFYRATV 391
            ||||:|||||||||||:||.||:.|.|.|||||||:|||||||.::.|.||::||::.:.|:...
Mouse   322 PLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVYNKSAWRHYQTIQ 386

  Fly   392 PTGDWSNQSSD 402
            ..|||...|::
Mouse   387 EAGDWCVPSTE 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdk	NP_001097240.1	BCDHK_Adom3	32..193	CDD:463093	100/164 (61%)
		HATPase_PDK-like	197..366	CDD:340406	100/168 (60%)
Pdk2	NP_598428.2	BCDHK_Adom3	30..192	CDD:463093	100/164 (61%)
		HATPase_PDK-like	196..361	CDD:340406	100/168 (60%)