Protein Alignment Pdk and pdhk-2

DIOPT Version :10

• Sequence 1: NP_001097240.1
• Gene: Pdk / 35970
• FlyBaseID: FBgn0017558
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_498928.1
• Gene: pdhk-2 / 176226
• WormBaseID: WBGene00022719
• Length: 401
• Species: Caenorhabditis elegans
• Alignment Length: 396
• Identity: 210/396 - (53%)
• Similarity: 284/396 - (71%)
• Gaps: 10/396 - (2%)

  Fly     6 VRFS--AASSSMASLAKMLDFYSGFNPSPLSIKQFMDFGQNACEKKSYIFLRKELPVRLANIMKE 68
            :|||  .....:.||||.||:||.|.||.|:|:|::|||:......||.||:.||.|||||||:|
 Worm     1 MRFSRKLLGPFVGSLAKKLDYYSQFQPSSLTIQQYLDFGRIGTSANSYTFLKNELLVRLANIMQE 65

  Fly    69 IALLPDNLLHTRSVSEVSSWYVKSFEDVLVYEKAEPTHDNLQKFVADLDLIRNRHNDVVQTMAQG 133
            ..|||..||...|...||:||.:||||:|::|.::.:.:.:.:|...|.::..||..||:|||:|
 Worm    66 FTLLPPKLLQMPSSKMVSNWYAESFEDLLLFEASDSSPEQVARFNDQLTVVLKRHAHVVETMAEG 130

  Fly   134 VIEMKENEGGQVDAPTESSIQYFLDRLYMSRISIRMLINQHTLLFGGNPHAGGRHIGCLDPACDL 198
            :||::|::|  ||..:|..|||||||.|::|||||||.|||.::||.......||:||:|||||:
 Worm   131 LIELRESDG--VDIASEKGIQYFLDRFYINRISIRMLQNQHLVVFGNVLPESPRHVGCIDPACDV 193

  Fly   199 SDVVRDAYENARFLCDQYYLTSPALEIQQHSS-EPGDNLPIRTVYVPSHLYYMLFELFKNSMRAV 262
            ..||.||:||||||||:||||||:::::.|:: |.|.  ||..|.||||||:|:||||||:|||.
 Worm   194 ESVVYDAFENARFLCDRYYLTSPSMKLEMHNAVEKGK--PISIVAVPSHLYHMMFELFKNAMRAT 256

  Fly   263 VEHHGHDNNDTLPPLKVAICKGKEDICVKISDQGGGIPRSQTDQLFKYMYSTAPQPSKSDLHTVP 327
            ||:||.|  |.||.:||.:.||:||:.:||.|:|||:.|:..::|:.|||||||.|.: |....|
 Worm   257 VEYHGVD--DDLPDIKVYVVKGQEDLSIKICDRGGGVSRTILERLYNYMYSTAPPPPR-DGTQAP 318

  Fly   328 LAGYGYGLPISRLYARYFHGDIVLLSCEGFGTDAIIYLKALSDEANELLPIFNKTSSKFYRATVP 392
            |||||||||:||||||||.||:.|:|.||.||||.|||||:..||:|:|||::.:|.:.......
 Worm   319 LAGYGYGLPLSRLYARYFLGDLFLVSMEGHGTDACIYLKAVPVEASEVLPIYSTSSRRNLTMGPQ 383

  Fly   393 TGDWSN 398
            ..|||:
 Worm   384 VADWSH 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdk	NP_001097240.1	BCDHK_Adom3	32..193	CDD:463093	77/160 (48%)
		HATPase_PDK-like	197..366	CDD:340406	102/169 (60%)
pdhk-2	NP_498928.1	BCDHK_Adom3	30..188	CDD:463093	77/159 (48%)
		HATPase_PDK-like	192..357	CDD:340406	102/169 (60%)