Protein Alignment Pdk and Pdk1

DIOPT Version :10

• Sequence 1: NP_001097240.1
• Gene: Pdk / 35970
• FlyBaseID: FBgn0017558
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_446278.2
• Gene: Pdk1 / 116551
• RGDID: 69427
• Length: 434
• Species: Rattus norvegicus
• Alignment Length: 405
• Identity: 226/405 - (55%)
• Similarity: 294/405 - (72%)
• Gaps: 16/405 - (3%)

  Fly     9 SAASSSMAS---LAKMLDFYSGFNPSPLSIKQFMDFGQ-NACEKKSYIFLRKELPVRLANIMKEI 69
            ||:.|..||   :...:|||:.|:|||||:|||:|||. |||||.|::|||:|||||||||||||
  Rat    30 SASGSGPASESGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEI 94

  Fly    70 ALLPDNLLHTRSVSEVSSWYVKSFEDVLVY-EKAEPTHDNLQKFVADLDLIRNRHNDVVQTMAQG 133
            :|||||||.|.||..|.|||::|.:::|.: :|:......:.:|...:..||||||||:.|||||
  Rat    95 SLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKTIYEFTDTVIRIRNRHNDVIPTMAQG 159

  Fly   134 VIEMKENEGGQVDAPTESSIQYFLDRLYMSRISIRMLINQHTLLFGGNPHAGGR-HIGCLDPACD 197
            |.|.||:.|  ||..|..::||||||.||||||||||:|||:|||||......| |||.::|.||
  Rat   160 VTEYKESFG--VDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGSPSHRKHIGSINPNCD 222

  Fly   198 LSDVVRDAYENARFLCDQYYLTSPALEIQQ-HSSEPGDNLPIRTVYVPSHLYYMLFELFKNSMRA 261
            :.:|::|.|||||.|||.||:.||.||::: ::..||.  ||:.||||||||:|:||||||:|||
  Rat   223 VVEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQ--PIQVVYVPSHLYHMVFELFKNAMRA 285

  Fly   262 VVEHHGHDNNDTLPPLKVAICKGKEDICVKISDQGGGIPRSQTDQLFKYMYSTAPQPSKSDLHTV 326
            .:|||.  :....||::|.:..|:||:.||:||:|||:|..:.|:||.|||||||:|.......|
  Rat   286 TMEHHA--DKGVYPPIQVHVTLGEEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAV 348

  Fly   327 PLAGYGYGLPISRLYARYFHGDIVLLSCEGFGTDAIIYLKALSDEANELLPIFNKTSSKFYRATV 391
            ||||:|||||||||||:||.||:.|.|.||:||||:||:||||.|:.|.||::||.:.|.||...
  Rat   349 PLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTESIERLPVYNKAAWKHYRTNH 413

  Fly   392 PTGDW---SNQSSDM 403
            ...||   |.:..||
  Rat   414 EADDWCVPSREPKDM 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdk	NP_001097240.1	BCDHK_Adom3	32..193	CDD:463093	98/163 (60%)
		HATPase_PDK-like	197..366	CDD:340406	97/169 (57%)
Pdk1	NP_446278.2	BCDHK_Adom3	56..218	CDD:463093	98/163 (60%)
		HATPase_PDK-like	222..388	CDD:340406	97/169 (57%)