Protein Alignment Pdk and BCKDK

DIOPT Version :9

• Sequence 1: NP_001097240.1
• Gene: Pdk / 35970
• FlyBaseID: FBgn0017558
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_005872.2
• Gene: BCKDK / 10295
• HGNCID: 16902
• Length: 412
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 100/335 - (29%)
• Similarity: 164/335 - (48%)
• Gaps: 41/335 - (12%)

  Fly    49 KSYIFLRKELPVRLANIMKEIALLPDNLLHTRSVSEVSSWYVKSFEDVLVYEKAEPTHDNLQKFV 113
            ||..:|::|||||:|:.:|....||..:....::..|...|:::|:.:..:...:...|..|.
Human    89 KSARYLQQELPVRIAHRIKGFRCLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEAQY-- 151

  Fly   114 ADLDLIR---NRHNDVVQTMAQGVIEMKENEGGQVDAPTESSIQYFLDRLYMSRISIRMLINQHT 175
              ..|:|   :.|.|||..:|:|:.|.:::      ...|..::||||:...||:.||||...|.
Human   152 --CQLVRQLLDDHKDVVTLLAEGLRESRKH------IEDEKLVRYFLDKTLTSRLGIRMLATHHL 208

  Fly   176 LLFGGNPHAGGRHIGCLDPACDLSDVVRDAYENARFLCDQYYLTSPALEIQQHSSEPGDNLPIRT 240
            .|....|.    .:|.:........::....:.||.||:..|..:|.:.|..|       :..|.
Human   209 ALHEDKPD----FVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGH-------VAARF 262

  Fly   241 VYVPSHLYYMLFELFKNSMRAVVEHHGHDNNDTLPPLKVAICKGKEDICVKISDQGGGIPRSQTD 305
            .::|..|.|:|.||.||:|||.:|.| .|....:|.:.:.|.....|:.::|||:||||.....|
Human   263 PFIPMPLDYILPELLKNAMRATMESH-LDTPYNVPDVVITIANNDVDLIIRISDRGGGIAHKDLD 326

  Fly   306 QLFKYMYSTAPQPSKS----------DLH----TVPLAGYGYGLPISRLYARYFHGDIVLLSCEG 356
            ::..|.::||...::.          |:|    :.|:.|:|:|||.||.||.|..|.:.|.|.:|
Human   327 RVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSLQG 391

  Fly   357 FGTDAIIYLK 366
            .|||  :||:
Human   392 IGTD--VYLR 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdk	NP_001097240.1	BCDHK_Adom3	32..193	CDD:402181	41/146 (28%)
		HATPase_PDK-like	197..366	CDD:340406	58/182 (32%)
BCKDK	NP_005872.2	BCDHK_Adom3	69..222	CDD:313630	41/146 (28%)
		HATPase_c	266..401	CDD:214643	50/137 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1242599at2759
OrthoFinder	1	1.000	-	-		FOG0000382
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920