DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pdk and bckdk

DIOPT Version :9

Sequence 1:	NP_001097240.1	Gene:	Pdk / 35970	FlyBaseID:	FBgn0017558	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	XP_002940756.2	Gene:	bckdk / 100380070	XenbaseID:	XB-GENE-994837	Length:	413	Species:	Xenopus tropicalis

Alignment Length:	402	Identity:	109/402 - (27%)
Similarity:	184/402 - (45%)	Gaps:	57/402 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRLFPVR---FSAASSSMASLAK-----MLDFY--SGFN-----------PSPLSIKQFMDFGQN 44
            :.|.|:|   .||...:...||:     :..||  ||.:           |:.:........|.:
Frog    22 LSLLPIRSRSTSATDQNHVELARERSKTVTSFYNQSGIDISAEKASVRLTPTTMLYSGRSQDGSH 86

  Fly    45 ACEKKSYIFLRKELPVRLANIMKEIALLPDNLLHTRSVSEVSSWYVKSFEDVLVYEKAEPTHDNL 109
            ..:...|::  ||||||:::.:|....||..:....::..|...|:::|:.:..:.... .|:..
Frog    87 ILKSARYLY--KELPVRISHRIKGFRSLPFIIGCNPTILHVHELYIRAFQKLSEFPPIS-NHETE 148

  Fly   110 QKFVADLDLIRNRHNDVVQTMAQGVIEMKENEGGQVDAPTESSIQYFLDRLYMSRISIRMLINQH 174
            .::...|..:.:.|.|||..:|:|:.|.:::      ...|..|:||||:...||:.||||...|
Frog   149 SQYCKLLRQLLDDHKDVVTQLAEGMRESRKH------IQDEKVIRYFLDKTLTSRLGIRMLATHH 207

  Fly   175 TLLFGGNPHAGGRHIGCLDPACDLSDVVRDAYENARFLCDQYYLTSPALEIQQHSSEPGDNLPIR 239
            ..|....|.    .:|.:........::....:.||.||:..|..:|.:.|..|       :..|
Frog   208 LALHEDRPD----FVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGH-------VAAR 261

  Fly   240 TVYVPSHLYYMLFELFKNSMRAVVEHHGHDNNDTLPPLKVAICKGKEDICVKISDQGGGIPRSQT 304
            ..::|..|.|:|.||.||||||.:|.| .:....:|.:.:.|.....|..::|||:|||||....
Frog   262 FPFIPMPLDYILPELLKNSMRATMESH-IETPYNVPDISITIANNDIDFIIRISDRGGGIPHDHM 325

  Fly   305 DQLFKYMYSTAPQPSKS-----------DL----HTVPLAGYGYGLPISRLYARYFHGDIVLLSC 354
            :::..|.::||...::.           |:    .:.|:.|:|:|||.||.||.|..|.:.:.|.
Frog   326 ERVMDYHFTTAETSAQDPRINPIFGNMVDMVNSGQSGPMHGFGFGLPTSRAYAEYLGGSLCIQSL 390

  Fly   355 EGFGTDAIIYLK 366
            :|.||||.:.||
Frog   391 QGIGTDAYLRLK 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdk	NP_001097240.1	BCDHK_Adom3	32..193	CDD:402181	39/160 (24%)
Pdk	NP_001097240.1	HATPase_PDK-like	197..366	CDD:340406	56/183 (31%)
bckdk	XP_002940756.2	BCDHK_Adom3	69..222	CDD:402181	40/165 (24%)
bckdk	XP_002940756.2	HATPase_PDK-like	226..402	CDD:340406	56/183 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1242599at2759
OrthoFinder	1	1.000	-	-		FOG0000382
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010