back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wun and PLPP3

DIOPT Version :9

Sequence 1:	NP_724787.1	Gene:	wun / 35966	FlyBaseID:	FBgn0016078	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_003704.3	Gene:	PLPP3 / 8613	HGNCID:	9229	Length:	311	Species:	Homo sapiens

Alignment Length:	301	Identity:	126/301 - (41%)
Similarity:	172/301 - (57%)	Gaps:	38/301 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 NKRILCRVGLDVLILLCAGFPILLFFLLGE-----PYKRGFFCDDESLKHPFH-DSTVRNWMLYF 141
            :||:|. :.||:..|..||.|    ||:.|     ||.|||:|:|||:|:|.. ..|:.:.:|..
Human    31 SKRVLL-ICLDLFCLFMAGLP----FLIIETSTIKPYHRGFYCNDESIKYPLKTGETINDAVLCA 90

  Fly   142 IGAVIPVGVIFIVEV--IISQNKAKQDNGNATSRRYVFMNYELPDWMIECYKKIGIYAFGAVLSQ 204
            :|.||.:..|...|.  |....|::....|              .::...||::|.:.||..:||
Human    91 VGIVIAILAIITGEFYRIYYLKKSRSTIQN--------------PYVAALYKQVGCFLFGCAISQ 141

  Fly   205 LTTDIAKYSIGRLRPHFIAVCQPQMADGSTCDDAINAGK-YIQEFTCKGVGSSARMLKEMRLSFP 268
            ..|||||.|||||||||::||.|..:.       ||..: |||.:.|:|..|.   ::|.|.||.
Human   142 SFTDIAKVSIGRLRPHFLSVCNPDFSQ-------INCSEGYIQNYRCRGDDSK---VQEARKSFF 196

  Fly   269 SGHSSFTFFAMVYLALYLQARMTWRGSKLLRHLLQFLFIMVAWYTALSRVSDYKHHWSDVLAGSL 333
            |||:||:.:.|:||.||||||.||||::|||.||||..||:|:||.||||||:|||.||||||..
Human   197 SGHASFSMYTMLYLVLYLQARFTWRGARLLRPLLQFTLIMMAFYTGLSRVSDHKHHPSDVLAGFA 261

  Fly   334 IGSISALVVANYVSDLFQKPNTKPYLARTVQDMNASPAQAI 374
            .|::.|..:..:|||||:...|....|..::....||...|
Human   262 QGALVACCIVFFVSDLFKTKTTLSLPAPAIRKEILSPVDII 302

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.