DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun and DPP1

DIOPT Version :9

Sequence 1:	NP_724787.1	Gene:	wun / 35966	FlyBaseID:	FBgn0016078	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_010570.1	Gene:	DPP1 / 851878	SGDID:	S000002692	Length:	289	Species:	Saccharomyces cerevisiae

Alignment Length:	252	Identity:	73/252 - (28%)
Similarity:	119/252 - (47%)	Gaps:	43/252 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 VLILLCAGFPILLFFLLGEPYKRGFFCDDESLKHPFHDS-TVRNWMLYFIGAVIPVGVIFIVEVI 157
            ::|::...:|:    ...:|::|.|:.:|.::.||:..: .|.|.||:....|:|...|.|:..|
Yeast    25 LIIMILLNYPV----YYQQPFERQFYINDLTISHPYATTERVNNNMLFVYSFVVPSLTILIIGSI 85

  Fly   158 ISQNKAKQDNGNATSRRYVFMNYELPDWMIECYKKIGIYAFGAVLSQLTTDIAKYSIGRLRPHFI 222
            :           |..|..:|:.|.         ..:|: :.....:...|:..|..||||||.|:
Yeast    86 L-----------ADRRHLIFILYT---------SLLGL-SLAWFSTSFFTNFIKNWIGRLRPDFL 129

  Fly   223 AVCQPQMADGSTCDDAINAGKYIQEFTCKGVGSS---ARMLKEMRLSFPSGHSSFTFFAMVYLAL 284
            ..|||  .:|...|..         ||.|.|.::   .|:|...|.: ||||||.:|..:.||..
Yeast   130 DRCQP--VEGLPLDTL---------FTAKDVCTTKNHERLLDGFRTT-PSGHSSESFAGLGYLYF 182

  Fly   285 YLQARMTWRG--SKLLRHLLQFLFIMVAWYTALSRVSDYKHHWSDVLAGSLIGSISA 339
            :|..::....  ..|.|.::.||.::.|...||||..||:||:.||:.||::|.|.|
Yeast   183 WLCGQLLTESPLMPLWRKMVAFLPLLGAALIALSRTQDYRHHFVDVILGSMLGYIMA 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun	NP_724787.1	PAP2_wunen	188..343	CDD:239479	52/157 (33%)
DPP1	NP_010570.1	PAP2_containing_1_like	50..245	CDD:239484	67/223 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46697
orthoMCL	1	0.900	-	-		OOG6_100228
Panther	1	1.100	-	-	O	PTHR10165
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3374
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840