DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun and Plppr3

DIOPT Version :9

Sequence 1:	NP_724787.1	Gene:	wun / 35966	FlyBaseID:	FBgn0016078	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_853665.2	Gene:	Plppr3 / 314614	RGDID:	727823	Length:	716	Species:	Rattus norvegicus

Alignment Length:	303	Identity:	84/303 - (27%)
Similarity:	137/303 - (45%)	Gaps:	65/303 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 LCAGFPILLFFL----LGEPYKRGFFCDDESLKHPF---HDSTVRNWMLYFIGAVIPVGVIFIVE 155
            :.|...:.|:||    |.:|.|.||.|.|.||..|:   ::..:...||..:....|...|.:.|
  Rat    28 IVASSVVSLYFLELTDLFQPAKVGFQCHDRSLSMPYVETNEELIPLLMLLSLAFAAPAASIMVGE 92

  Fly   156 --VIISQNK--------------AKQDNGNATSRRYVFMNYELPDWMIECYKKIGIYAFGAVLSQ 204
              |...|::              |...|.|:..||.|              :.:|::.||...:.
  Rat    93 GMVYCLQSRLWGRGPGGVEGSINAGGCNFNSFLRRTV--------------RFVGVHVFGLCATA 143

  Fly   205 LTTDIAKYSIGRLRPHFIAVCQPQMA-DGSTCDDAINAGKYIQEFTCKGVGSSARMLKEMRLSFP 268
            |.||:.:.:.|...|.|:.||:|... .|::|:    |..||.:..|.|..:.|  :...|.:||
  Rat   144 LVTDVIQLATGYHTPFFLTVCKPNYTLLGTSCE----ANPYITQDICSGHDTHA--ILSARKTFP 202

  Fly   269 SGHSSFTFFAMVYLALYLQARMTWRGSKLLRHLLQFLFIMVAWYTALSRVSDYKHHWSDVLAGSL 333
            |.|::.:.||.||:::|..:.:: ..:|||:.:|.|.|.:.|....|::::.|:.|..||.||.|
  Rat   203 SQHATLSAFAAVYVSMYFNSVIS-DATKLLKPILVFAFAIAAGVCGLTQITQYRSHPVDVYAGFL 266

  Fly   334 IGS-ISALVVANYVSDLFQKPNTKPYLA-RTVQDMNASPAQAI 374
            ||: |:|                  ||| ..|.:..||||:.:
  Rat   267 IGAGIAA------------------YLACHAVGNFQASPAEKV 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun	NP_724787.1	PAP2_wunen	188..343	CDD:239479	49/156 (31%)
Plppr3	NP_853665.2	PAP2_wunen	127..276	CDD:239479	52/187 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	311..334
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	416..488
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	548..589
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	664..694
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338368
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740