DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun and Plpp1

DIOPT Version :9

Sequence 1:	NP_724787.1	Gene:	wun / 35966	FlyBaseID:	FBgn0016078	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_032273.1	Gene:	Plpp1 / 19012	MGIID:	108412	Length:	284	Species:	Mus musculus

Alignment Length:	305	Identity:	122/305 - (40%)
Similarity:	175/305 - (57%)	Gaps:	34/305 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 NKRILCRVGLDVLILLCAGFPILLFFLLGE--PYKRGFFCDDESLKHPFHDSTVRNWMLYFIGAV 145
            :|..|..|.|||:.:|.|..|:.: ..||:  |::|||||.|.|:|:|:||||:.:.:|..:|..
Mouse     3 DKTRLPYVALDVICVLLAAMPMTI-LKLGKVYPFQRGFFCTDNSVKYPYHDSTIPSRILAILGLG 66

  Fly   146 IPVGVIFIVEVIISQNKAKQDN---GNATSRRYVFMNYELPDWMIECYKKIGIYAFGAVLSQLTT 207
            :|:..:.|.|.:.........|   ||              .::...||.:|.:.||...||..|
Mouse    67 LPIFSMSIGESLSVYFNVLHSNSFVGN--------------PYIATIYKAVGAFLFGVSASQSLT 117

  Fly   208 DIAKYSIGRLRPHFIAVCQPQMADGSTCDDAINAGKYIQEFTCKGVGSSARMLKEMRLSFPSGHS 272
            |||||:||.|||||:|:|.|..:. ..|.|.     ||:::.|:|   :...:||.||||.||||
Mouse   118 DIAKYTIGSLRPHFLAICNPDWSK-INCSDG-----YIEDYICQG---NEEKVKEGRLSFYSGHS 173

  Fly   273 SFTFFAMVYLALYLQARMTWRGSKLLRHLLQFLFIMVAWYTALSRVSDYKHHWSDVLAGSLIGSI 337
            ||:.:.|:::||||||||....::|||.:|||..|..:.|..||||||||||||||..|.:.|:.
Mouse   174 SFSMYCMLFVALYLQARMKGDWARLLRPMLQFGLIAFSIYVGLSRVSDYKHHWSDVTVGLIQGAA 238

  Fly   338 SALVVANYVSDLFQKPNTKPYLARTVQDMNAS---PAQAITITTN 379
            .|::||.||||.|:  :|..|..|..:|.:.:   .|.:...:||
Mouse   239 MAILVALYVSDFFK--DTHSYKERKEEDPHTTLHETASSRNYSTN 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun	NP_724787.1	PAP2_wunen	188..343	CDD:239479	75/154 (49%)
Plpp1	NP_032273.1	PAP2_wunen	99..244	CDD:239479	75/153 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834749
Domainoid	1	1.000	159	1.000	Domainoid score	I4068
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	204	1.000	Inparanoid score	I3731
Isobase	1	0.950	-	0	Normalized mean entropy	S2766
OMA	1	1.010	-	-		QHG48083
OrthoDB	1	1.010	-	-		D434801at33208
OrthoFinder	1	1.000	-	-		FOG0000694
OrthoInspector	1	1.000	-	-		mtm8794
orthoMCL	1	0.900	-	-		OOG6_100228
Panther	1	1.100	-	-	LDO	PTHR10165
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3374
SonicParanoid	1	1.000	-	-		X571
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.750