Protein Alignment Non1 and Gtpbp4

DIOPT Version :10

• Sequence 1: NP_610484.1
• Gene: Non1 / 35963
• FlyBaseID: FBgn0028473
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_081276.2
• Gene: Gtpbp4 / 69237
• MGIID: 1916487
• Length: 634
• Species: Mus musculus
• Alignment Length: 662
• Identity: 392/662 - (59%)
• Similarity: 483/662 - (72%)
• Gaps: 38/662 - (5%)

  Fly     1 MSLYNFKKIMVVPPAKDFIDIMLSKTQRKTPTVVHKGYKISRIRAFYTRKVKYTQQNFHDRLSQI 65
            |:.||||||.|||.||||||:.|||||||||||:||.|:|.|||.||.||||:||||:|||||||
Mouse     1 MAHYNFKKITVVPSAKDFIDLTLSKTQRKTPTVIHKHYQIHRIRHFYMRKVKFTQQNYHDRLSQI 65

  Fly    66 IQDFPKLDDVHPFYADLMNVLYDKDHYKLALGQLNTARHLVDNVAKDYVRLLKYGDSLYRCKQLK 130
            :.|||||||:|||||||||:|||||||||||||:|.|::||||||||||||:|||||||||||||
Mouse    66 LSDFPKLDDIHPFYADLMNILYDKDHYKLALGQINIAKNLVDNVAKDYVRLMKYGDSLYRCKQLK 130

  Fly   131 KAALGRMATIMKRQASNLTYLEQVRQHLSRLPTIDPYSRTIIICGFPNVGKSSFINKITRADVEV 195
            :||||||.||:|||..:|.|||||||||||||||||.:||:::||:|||||||||||:|||||:|
Mouse   131 RAALGRMCTIIKRQRQSLEYLEQVRQHLSRLPTIDPNTRTLLLCGYPNVGKSSFINKVTRADVDV 195

  Fly   196 QPYAFTTKSLYVGHTDYKYLRWQVIDTPGILDHPLEERNVIEMQAITALAHLRACVLYFMDISEQ 260
            ||||||||||:|||.|||||||||:|||||||||||:||.||||||||||||||.|||.||:|||
Mouse   196 QPYAFTTKSLFVGHMDYKYLRWQVVDTPGILDHPLEDRNTIEMQAITALAHLRAAVLYVMDLSEQ 260

  Fly   261 CGHSLEEQVKLFESIKPLFTNKPLILAINKIDILTPEDLPEERRAIITKLQEDKNIPVMLMSTVQ 325
            |||.|:||::||::|:|||.|||||:..||.|:....:|.||.:.|...||.: ..||:..||:.
Mouse   261 CGHGLKEQLELFQNIRPLFINKPLIVVANKCDVKRIAELSEEDQKIFLDLQAE-GFPVIETSTLT 324

  Fly   326 ETGVMEVKTEACERLLSYRVDQKMRTKKVDNILNRLHVAMPAPRDDKLRAPCIPEKASARLLQNA 390
            |.||::||||||:|||::||:.||:..||:.:|||||:|:|..||||.|.|.|||...|| .:..
Mouse   325 EEGVIQVKTEACDRLLAHRVETKMKGNKVNEVLNRLHLAVPNKRDDKERPPFIPEGVIAR-RKRM 388

  Fly   391 DKAERKRKLEKEIEEEMGDDYTLDLKKNYSEIPEEERYDIIPEFWQGHNIADYIDADIFDKLEEL 455
            :..|.|:|.|:::|.||||||.|||:|.:..:...|:||.|||.|:|||:|||||..|..|||||
Mouse   389 EIEEPKKKRERDLELEMGDDYILDLQKYWDLMNSSEKYDKIPEIWEGHNVADYIDPAIMKKLEEL 453

  Fly   456 EREEGLREESGVYKVPDMTMDETLKEIREIAKQIRGKRFELRDEKRL----SSRKNK--PVIPRN 514
            |:||.||..:|.|.....:.||.:.|||::||||       |::|:|    |..|||  |.:||.
Mouse   454 EKEEELRTAAGEYDSDSESEDEEMMEIRQLAKQI-------REKKKLKILQSKEKNKQGPRMPRT 511

  Fly   515 KQPKVRDRSVQK--LVSTMEGLGVDMSGSENANFTKSVVDLRRGQVAVGSKKVPMQPLLDKESSA 577
            .      :.||:  |.:.|..|||||....||::   .|..||.:.....:|        :|.|.
Mouse   512 A------KKVQRADLENEMRSLGVDMDDKNNAHY---AVQARRSRSVTRKRK--------REESV 559

  Fly   578 VVRKT--GQPLKRAPSRDTLGIKNLAIRKKAQIMAKRDIAKKVTSRGLKGEADRFIGTKMPKHLF 640
            ....|  .:...|.| ||..|::::.:.|||:.|.|: ..||:...|.||||||.:....||||.
Mouse   560 PPSSTARSRSCSRTP-RDVSGLRDVKMVKKAKTMMKK-AQKKMNRLGKKGEADRHVFDMKPKHLL 622

  Fly   641 SGKRGNGKTDRR 652
            ||||..||.|||
Mouse   623 SGKRKAGKKDRR 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Non1	NP_610484.1	Nog1	6..340	CDD:440701	250/333 (75%)
		NOGCT	400..448	CDD:462381	27/47 (57%)
Gtpbp4	NP_081276.2	Nog1	6..339	CDD:440701	250/333 (75%)
		NOGCT	398..446	CDD:462381	27/47 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	494..634		55/158 (35%)