Protein Alignment CG8800 and LRRC46

DIOPT Version :9

• Sequence 1: NP_610483.1
• Gene: CG8800 / 35962
• FlyBaseID: FBgn0033408
• Length: 188
• Species: Drosophila melanogaster
• Sequence 2: XP_005257832.1
• Gene: LRRC46 / 90506
• HGNCID: 25047
• Length: 330
• Species: Homo sapiens
• Alignment Length: 137
• Identity: 46/137 - (33%)
• Similarity: 70/137 - (51%)
• Gaps: 9/137 - (6%)

  Fly    46 TLVQCERISMSTNMIEKIFGLSGMKCLKVLSLSRNYIKQISGLEAVAETLEELWLSYNLIEKIKG 110
            ||.:.:.:.:....|..|..|.|::.|..|.|..|.|:||..| |...:|..|.|:.|.|.:::.
Human    51 TLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENL-ACIPSLRFLSLAGNQIRQVEN 114

  Fly   111 LTGLKCLKVLYISNNLIKDWSEFNRLAEI-ESLEDLVVVGNPLSEGLDEPTWRAECIKRLPTIRK 174
            |..|.||:.|.:|.|||    |..:|.|. :||..|.:.||..:   ::..:|....:.||.:..
Human   115 LLDLPCLQFLDLSENLI----ETLKLDEFPQSLLILNLSGNSCT---NQDGYRELVTEALPLLLD 172

  Fly   175 LDGEPVV 181
            |||:|||
Human   173 LDGQPVV 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	43/134 (32%)
		leucine-rich repeat	50..71	CDD:275380	4/20 (20%)
		leucine-rich repeat	95..116	CDD:275380	7/20 (35%)
		leucine-rich repeat	117..141	CDD:275380	9/24 (38%)
LRRC46	XP_005257832.1	LRR_8	54..109	CDD:290566	17/55 (31%)
		leucine-rich repeat	55..76	CDD:275378	4/20 (20%)
		LRR_4	75..115	CDD:289563	14/40 (35%)
		leucine-rich repeat	77..98	CDD:275378	9/21 (43%)
		LRR_8	97..151	CDD:290566	20/57 (35%)
		LRR_4	97..135	CDD:289563	15/41 (37%)
		leucine-rich repeat	99..120	CDD:275378	7/20 (35%)
		leucine-rich repeat	121..142	CDD:275378	9/24 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900