DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8800 and NUD1

DIOPT Version :9

Sequence 1:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_015018.3	Gene:	NUD1 / 854555	SGDID:	S000005900	Length:	851	Species:	Saccharomyces cerevisiae

Alignment Length:	220	Identity:	58/220 - (26%)
Similarity:	93/220 - (42%)	Gaps:	49/220 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TTIKEALKRWEEREQQ--NSLTAKVI---DLQFQWPPIEKMDSTLGTLVQ---CER-------IS 54
            |:|.|....:.|.|:|  :.||:|:.   .....|..|.|:|.:.|.|..   .:|       ::
Yeast   442 TSISEVNTSFNETEKQLISILTSKLSGSPSYDSDWEKILKVDLSRGKLKNMFGMQRLLPNVLVLN 506

  Fly    55 MSTNMIEKIFG---------------------LSGMKCLKVLSLSRNYIKQISGLEAVAETLEEL 98
            :|.|.:..:.|                     |:|...|:.|.||.|.:.......::...|:|:
Yeast   507 LSDNEMNTLEGIPSNVVQLFCSNNKITSAHCSLAGFHDLECLDLSYNLLNTSLKFLSLCHHLQEV 571

  Fly    99 WLSYNLIEKIKGLTGLKCLKVLYISNNLIKDWSEFNRLAEIESLEDLVVVGNPLS-EGLDEP--- 159
            .||||.|:.::|: |...:|.|.:|||.|....:|.:|.    |.:..|||..|: |.||..
Yeast   572 NLSYNSIQSLEGI-GSSRMKKLNLSNNEINGIIDFEQLI----LTNNSVVGGWLTVEVLDLSNNN 631

  Fly   160 ---TWRAECIKRLPTIRKLDGEPVV 181
               .....|:.||..: .|:|.|:|
Yeast   632 IIGVRNINCLPRLKVL-NLNGNPLV 655

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	46/180 (26%)
		leucine-rich repeat	50..71	CDD:275380	6/48 (13%)
		leucine-rich repeat	95..116	CDD:275380	9/20 (45%)
		leucine-rich repeat	117..141	CDD:275380	8/23 (35%)
NUD1	NP_015018.3	LRR	<440..662	CDD:227223	58/220 (26%)
		leucine-rich repeat	522..544	CDD:275380	2/21 (10%)
		leucine-rich repeat	545..567	CDD:275380	5/21 (24%)
		PPP1R42	557..784	CDD:411060	32/105 (30%)
		leucine-rich repeat	568..588	CDD:275380	9/20 (45%)
		leucine-rich repeat	589..621	CDD:275380	12/35 (34%)
		leucine-rich repeat	622..643	CDD:275380	4/20 (20%)
		leucine-rich repeat	699..738	CDD:275380
		leucine-rich repeat	739..768	CDD:275380
		leucine-rich repeat	794..806	CDD:275378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900