DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8800 and Ppp1r7

DIOPT Version :9

Sequence 1:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_075689.1	Gene:	Ppp1r7 / 66385	MGIID:	1913635	Length:	361	Species:	Mus musculus

Alignment Length:	162	Identity:	48/162 - (29%)
Similarity:	82/162 - (50%)	Gaps:	30/162 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 IEKMDSTLGTLVQCERISMSTNMIEKIFGLSGMKCLKVLSLSRNYIKQISGLEAVAETLEELWLS 101
            ||.:|    ||...|.:.:..|.|.|:..|..:..|.|||:..|.:.:|.||:::. .|.||:||
Mouse   202 IENID----TLTNLESLFLGKNKITKLQNLDALTNLTVLSVQSNRLAKIEGLQSLV-NLRELYLS 261

  Fly   102 YNLIEKIKGL----------------------TGLKCLKVLYISNNLIKDWSEFNRLAEIESLED 144
            .|.||.|:||                      :.|..|:..::::||::.||:.:.|....|||.
Mouse   262 NNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLET 326

  Fly   145 LVVVGNPLSEGLDEPTWRAECIKRLPTIRKLD 176
            :.:..|||.:   :|.:|.:.:..||::|::|
Mouse   327 VYLERNPLQK---DPQYRRKVMLALPSVRQID 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	48/162 (30%)
		leucine-rich repeat	50..71	CDD:275380	5/20 (25%)
		leucine-rich repeat	95..116	CDD:275380	12/42 (29%)
		leucine-rich repeat	117..141	CDD:275380	6/23 (26%)
Ppp1r7	NP_075689.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..64
		LRR 1	78..99
		LRR_4	99..140	CDD:289563
		LRR 2	100..121
		leucine-rich repeat	101..122	CDD:275380
		LRR_4	121..163	CDD:289563
		LRR_8	122..177	CDD:290566
		LRR 3	122..143
		leucine-rich repeat	123..144	CDD:275380
		LRR_4	143..185	CDD:289563
		LRR 4	144..165
		leucine-rich repeat	145..166	CDD:275380
		LRR_8	165..221	CDD:290566	7/22 (32%)
		LRR 5	166..187
		leucine-rich repeat	167..188	CDD:275380
		LRR_4	188..227	CDD:289563	9/28 (32%)
		LRR 6	188..209		4/10 (40%)
		leucine-rich repeat	189..210	CDD:275380	5/11 (45%)
		LRR_4	209..251	CDD:289563	13/41 (32%)
		LRR 7	210..231		5/20 (25%)
		leucine-rich repeat	211..232	CDD:275380	5/20 (25%)
		LRR_8	231..287	CDD:290566	19/56 (34%)
		LRR 8	232..253		8/20 (40%)
		leucine-rich repeat	233..254	CDD:275380	8/21 (38%)
		LRR_4	254..295	CDD:289563	11/40 (28%)
		LRR 9	254..275		11/20 (55%)
		leucine-rich repeat	255..276	CDD:275380	11/20 (55%)
		LRR_4	276..317	CDD:289563	6/40 (15%)
		LRR 10	276..297		0/20 (0%)
		leucine-rich repeat	277..298	CDD:275380	1/20 (5%)
		LRR 11	298..319		5/20 (25%)
		LRRcap	337..355	CDD:197729	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810