DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8800 and LRRC61

DIOPT Version :9

Sequence 1:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_001136400.1	Gene:	LRRC61 / 65999	HGNCID:	21704	Length:	259	Species:	Homo sapiens

Alignment Length:	146	Identity:	40/146 - (27%)
Similarity:	71/146 - (48%)	Gaps:	33/146 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 LGTLVQC---ERISMSTNMIEKIFGLSGMKCLKVLSLSRNYIKQISGLE--AVAETLEELWLSYN 103
            ||.|.:|   |.:.:|.|.:..:..|:.::.|.||::|.|   :::|||  |..|.|:.|..:.|
Human    46 LGCLGECLGLEWLDLSGNALTHLGPLASLRQLAVLNVSNN---RLTGLEPLATCENLQSLNAAGN 107

  Fly   104 LIE---KIKGLTGLKCLKVLYISNNLIKDWSEFNRLAEIESLEDLVVVGNPLSEGLDEPTWRAEC 165
            |:.   :::.|.||.||:.|.:.:.|.:                   :.|||..   .|::.|..
Human   108 LLATPGQLQCLAGLPCLEYLRLRDPLAR-------------------LSNPLCA---NPSYWAAV 150

  Fly   166 IKRLPTIRKLDGEPVV 181
            .:.||.::.:|||.|:
Human   151 RELLPGLKVIDGERVI 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	39/143 (27%)
		leucine-rich repeat	50..71	CDD:275380	5/23 (22%)
		leucine-rich repeat	95..116	CDD:275380	7/23 (30%)
		leucine-rich repeat	117..141	CDD:275380	3/23 (13%)
LRRC61	NP_001136400.1	LRR 1	32..53		3/6 (50%)
		LRR 2	54..75		4/20 (20%)
		leucine-rich repeat	55..76	CDD:275380	4/20 (20%)
		LRR_9	<58..165	CDD:317038	34/131 (26%)
		LRR 3	76..97		9/23 (39%)
		leucine-rich repeat	77..98	CDD:275380	9/23 (39%)
		LRR 4	98..119		4/20 (20%)
		leucine-rich repeat	99..123	CDD:275380	7/23 (30%)
		leucine-rich repeat	124..149	CDD:275380	7/46 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15454
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.000