DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8800 and ppp1r7

DIOPT Version :9

Sequence 1:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_001032463.1	Gene:	ppp1r7 / 560323	ZFINID:	ZDB-GENE-051113-288	Length:	345	Species:	Danio rerio

Alignment Length:	162	Identity:	47/162 - (29%)
Similarity:	84/162 - (51%)	Gaps:	30/162 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 IEKMDSTLGTLVQCERISMSTNMIEKIFGLSGMKCLKVLSLSRNYIKQISGLEAVAETLEELWLS 101
            ||.:||    |...|.:.:.||.|.::..|.|:..|.|||:..|.|.::.||:.:. .|.||:||
Zfish   186 IENLDS----LSSLESLFLGTNKITQLQNLDGLHNLTVLSIQSNRITKLEGLQNLV-NLRELYLS 245

  Fly   102 YNLIE----------------------KIKGLTGLKCLKVLYISNNLIKDWSEFNRLAEIESLED 144
            :|.||                      ||:.::.|..||..::::|.|::|::.:.|...:.||.
Zfish   246 HNGIEVMEGLENNKKLSTLDIAANRIKKIENISHLTDLKEFWMNDNQIENWADLDELKNAKGLET 310

  Fly   145 LVVVGNPLSEGLDEPTWRAECIKRLPTIRKLD 176
            :.:..|||.:   :|.:|.:.:..||::|::|
Zfish   311 VYLERNPLQK---DPQYRRKIMLALPSVRQID 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	47/162 (29%)
		leucine-rich repeat	50..71	CDD:275380	6/20 (30%)
		leucine-rich repeat	95..116	CDD:275380	11/42 (26%)
		leucine-rich repeat	117..141	CDD:275380	6/23 (26%)
ppp1r7	NP_001032463.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..53
		LRR 1	62..83
		LRR 2	84..105
		LRR_8	86..139	CDD:290566
		LRR_4	86..124	CDD:289563
		leucine-rich repeat	86..106	CDD:275380
		LRR_4	106..147	CDD:289563
		LRR 3	106..127
		leucine-rich repeat	107..128	CDD:275380
		LRR_4	127..169	CDD:289563
		LRR 4	128..149
		leucine-rich repeat	129..150	CDD:275380
		LRR 5	150..171
		leucine-rich repeat	151..172	CDD:275380
		LRR 6	172..193		4/10 (40%)
		leucine-rich repeat	173..216	CDD:275380	11/33 (33%)
		LRR 7	194..215		6/20 (30%)
		LRR_8	216..271	CDD:290566	16/55 (29%)
		LRR_4	216..257	CDD:289563	16/41 (39%)
		LRR 8	216..237		8/20 (40%)
		leucine-rich repeat	217..238	CDD:275380	8/21 (38%)
		LRR_4	238..279	CDD:289563	10/40 (25%)
		LRR 9	238..259		8/20 (40%)
		leucine-rich repeat	239..260	CDD:275380	8/20 (40%)
		LRR_4	259..301	CDD:289563	8/41 (20%)
		LRR 10	260..281		2/20 (10%)
		leucine-rich repeat	261..282	CDD:275380	3/20 (15%)
		LRR 11	282..303		5/20 (25%)
		leucine-rich repeat	283..307	CDD:275380	6/23 (26%)
		LRRcap	321..339	CDD:197729	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810