DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8800 and Lrriq3

DIOPT Version :9

Sequence 1:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_001019478.1	Gene:	Lrriq3 / 499732	RGDID:	1591943	Length:	633	Species:	Rattus norvegicus

Alignment Length:	192	Identity:	46/192 - (23%)
Similarity:	74/192 - (38%)	Gaps:	41/192 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKATTIKEALKRWEE---REQQNSLTAKVIDLQFQWPPIEKMDSTLGTLVQCERISMSTNMIEK 62
            ::|..|..|....:.|   .:|::.:..|...|..:  .:|.:.|.:...| |   ..|.|.:..
  Rat     6 ITKELTSHEEWSHYNENIVEDQKDFVFVKYNGLHLK--SMENLQSCISLRV-C---IFSNNFVTD 64

  Fly    63 IFGLSGMKCLKVLSLSRNYIKQISGLEAVAETLEE--LWLSYNLIEKIKGLTGLKCLKVLYISNN 125
            |..|.|.|.|..|.|..|.||          ||.:  .|            .|||.||:||:.:|
  Rat    65 IQPLQGCKKLIKLDLHGNQIK----------TLPDRTFW------------NGLKNLKLLYLHDN 107

  Fly   126 LIKDWSEFNRLAEIESLEDLVVVGNPLS--EGLDEPTWRAECIKRLPTIRKLDGEPVVLNEE 185
            ..........|:...:|..|.:...|:|  :|     :|...:..:..::.|| ..|:.:||
  Rat   108 GFAKLKNICVLSGCVNLVGLTMFDCPVSLKKG-----YRHVLVNSIWPLKALD-HHVISDEE 163

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	36/146 (25%)
		leucine-rich repeat	50..71	CDD:275380	6/20 (30%)
		leucine-rich repeat	95..116	CDD:275380	4/22 (18%)
		leucine-rich repeat	117..141	CDD:275380	6/23 (26%)
Lrriq3	NP_001019478.1	PPP1R42	36..>128	CDD:411060	30/119 (25%)
		LRR 1	51..72		7/24 (29%)
		leucine-rich repeat	52..73	CDD:275378	7/24 (29%)
		LRR 2	73..94		9/42 (21%)
		leucine-rich repeat	74..98	CDD:275378	11/45 (24%)
		LRR 3	98..119		5/20 (25%)
		leucine-rich repeat	99..115	CDD:275378	5/15 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	322..343
		DUF5401	<388..>586	CDD:375164
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900