DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8800 and ppp1r7

DIOPT Version :9

Sequence 1:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_001006731.1	Gene:	ppp1r7 / 448394	XenbaseID:	XB-GENE-964679	Length:	346	Species:	Xenopus tropicalis

Alignment Length:	158	Identity:	45/158 - (28%)
Similarity:	80/158 - (50%)	Gaps:	22/158 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 IEKMDS------------------TLGTLVQCERISMSTNMIEKIFGLSGMKCLKVLSLSRNYIK 83
            ||.:||                  .|.||.....:|:.:|.:.||.||..:..|:.|.||.|.|:
Frog   187 IENLDSLRELDSLFLGKNKITKLQNLETLTNLTVLSVQSNRLTKIEGLQNLVNLRELYLSDNGIQ 251

  Fly    84 QISGLEAVAETLEELWLSYNLIEKIKGLTGLKCLKVLYISNNLIKDWSEFNRLAEIESLEDLVVV 148
            .|.|||. ...|..|.|:.|.|::|:.:..|..|:..::::||:::||:...|:....|:.:.:.
Frog   252 VIEGLEN-NNKLTTLDLASNRIKRIENIKHLSELQEFWMNDNLVENWSDLEELSGAPGLQTVYLE 315

  Fly   149 GNPLSEGLDEPTWRAECIKRLPTIRKLD 176
            .|||.:   :..:|.:.:..||::|::|
Frog   316 RNPLQK---DAQYRRKIMLALPSVRQID 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	45/158 (28%)
		leucine-rich repeat	50..71	CDD:275380	6/20 (30%)
		leucine-rich repeat	95..116	CDD:275380	7/20 (35%)
		leucine-rich repeat	117..141	CDD:275380	6/23 (26%)
ppp1r7	NP_001006731.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..46
		internalin_A	46..>320	CDD:380193	39/133 (29%)
		LRR 1	63..84
		LRR 2	85..106
		leucine-rich repeat	86..104	CDD:275380
		LRR 3	107..128
		leucine-rich repeat	108..129	CDD:275380
		LRR 4	129..150
		leucine-rich repeat	130..151	CDD:275380
		LRR 5	151..172
		leucine-rich repeat	152..173	CDD:275380
		LRR 6	173..194		4/6 (67%)
		leucine-rich repeat	174..192	CDD:275380	2/4 (50%)
		leucine-rich repeat	193..217	CDD:275380	3/23 (13%)
		LRR 7	195..216		2/20 (10%)
		LRR 8	217..238		6/20 (30%)
		leucine-rich repeat	218..239	CDD:275380	6/20 (30%)
		LRR 9	239..260		10/21 (48%)
		leucine-rich repeat	240..261	CDD:275380	10/21 (48%)
		LRR 10	261..282		6/20 (30%)
		leucine-rich repeat	262..283	CDD:275380	7/20 (35%)
		LRR 11	283..304		5/20 (25%)
		LRRcap	322..340	CDD:197729	4/17 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910