DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8800 and Lrrc43

DIOPT Version :9

Sequence 1:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_001028633.1	Gene:	Lrrc43 / 381741	MGIID:	2685907	Length:	667	Species:	Mus musculus

Alignment Length:	169	Identity:	47/169 - (27%)
Similarity:	74/169 - (43%)	Gaps:	32/169 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 IEKMDSTLGTLVQCERISMSTNMIEKIFGLSGMKCLKVLSLSRNYIKQISGL-EAVAETLEELWL 100
            :..:|..|...::.|.:.:|.|.||:|...:....||||.|..|.|..:..| .|....|:.|.|
Mouse   136 VSLVDKDLLKFLKLEELVLSANKIEEIDANNLPPTLKVLELYGNLIASMECLCSAPPPRLQHLGL 200

  Fly   101 SYNLIEKIKGLTGLKCLKVLYISNNLIKDWSE-------FNRLAEIES----------LEDLVVV 148
            .:|.:        |..|:.||::::   :|.:       ||.|.::::          |..||:.
Mouse   201 GHNKL--------LGPLESLYVTSH---NWPQLVSLDLGFNNLTDLQNMILGLSTLRHLRLLVLQ 254

  Fly   149 GNPLSEGLDEPTWRAECIKRLPTIRKLDGEPVVLNEEPQ 187
            |||||.   .|.:|...|..|..:..||...|..||:.|
Mouse   255 GNPLSL---VPYYRGFTIDSLAHLCVLDDITVSPNEKHQ 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	43/160 (27%)
		leucine-rich repeat	50..71	CDD:275380	6/20 (30%)
		leucine-rich repeat	95..116	CDD:275380	5/20 (25%)
		leucine-rich repeat	117..141	CDD:275380	7/30 (23%)
Lrrc43	NP_001028633.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		LRR 1	148..169		6/20 (30%)
		LRR	<154..>263	CDD:227223	34/122 (28%)
		LRR 2	170..191		8/20 (40%)
		leucine-rich repeat	171..194	CDD:275378	9/22 (41%)
		LRR 3	194..213		6/26 (23%)
		leucine-rich repeat	195..221	CDD:275378	9/36 (25%)
		LRR 4	221..242		3/20 (15%)
		leucine-rich repeat	222..247	CDD:275378	3/24 (13%)
		leucine-rich repeat	248..259	CDD:275378	6/10 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	374..407
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	533..570
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	616..640
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900