DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8800 and Cntrl

DIOPT Version :9

Sequence 1:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	XP_006234114.1	Gene:	Cntrl / 311886	RGDID:	1305317	Length:	2336	Species:	Rattus norvegicus

Alignment Length:	191	Identity:	55/191 - (28%)
Similarity:	97/191 - (50%)	Gaps:	21/191 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IKEALKRWEEREQQNSLTAKVIDL--------QFQWPPIEKMDSTLGTLVQCERISMSTNMIEKI 63
            |.|||.: :..:|.|....|.::|        :|::  ||.::.    .|:.|.:::|.|:|.||
  Rat    83 ITEALIK-KLTKQDNLALVKSLNLSLSKDGGKKFRY--IENLEK----CVKLEVLNLSYNLIAKI 140

  Fly    64 FGLSGMKCLKVLSLSRNYIKQISGLEAVAETLEELWLSYNLIEKIKGLTG--LKCLKVLYISNNL 126
            ..:..:..|:.|:||.|.|.:|.|||.:. .|::|.|:.|.||.|.|...  ||.|:||.:..|.
  Rat   141 EKVDKLLRLRELNLSYNKISKIEGLENMC-NLQKLNLAGNEIEHIPGWFSKKLKSLRVLNLKGNK 204

  Fly   127 IKDWSEFNRLAEIESLEDLVVVGNPLSEGLDEPTWRAECIKRLPTIRKLDGEPVVLNEEPQ 187
            |....:.::|..::.|..|.::.||:   :..|.:....|..|.::..|:|:||...:..:
  Rat   205 ISSLQDVSKLKPLQDLTSLTLIDNPV---VALPHYLQFIIFHLRSLESLEGQPVTTQDRQE 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	44/144 (31%)
		leucine-rich repeat	50..71	CDD:275380	6/20 (30%)
		leucine-rich repeat	95..116	CDD:275380	9/22 (41%)
		leucine-rich repeat	117..141	CDD:275380	6/23 (26%)
Cntrl	XP_006234114.1	PPP1R42	89..261	CDD:411060	51/182 (28%)
		leucine-rich repeat	100..119	CDD:275378	3/20 (15%)
		leucine-rich repeat	127..148	CDD:275380	6/20 (30%)
		leucine-rich repeat	149..170	CDD:275380	10/21 (48%)
		leucine-rich repeat	171..194	CDD:275380	9/22 (41%)
		leucine-rich repeat	195..219	CDD:275380	6/23 (26%)
		leucine-rich repeat	220..246	CDD:275380	7/28 (25%)
		PTZ00108	<267..535	CDD:240271
		SMC_prok_B	<438..1120	CDD:274008
		Drf_FH1	1238..>1300	CDD:399386
		SMC_prok_B	1396..2215	CDD:274008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810