DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8800 and Cep97

DIOPT Version :9

Sequence 1:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_001100566.1	Gene:	Cep97 / 304007	RGDID:	1307400	Length:	845	Species:	Rattus norvegicus

Alignment Length:	188	Identity:	43/188 - (22%)
Similarity:	76/188 - (40%)	Gaps:	61/188 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 LGTLVQCE---RISMSTNMIEKIFGLSGMKCLKVLSLSRNYIKQISGLEAV-------------- 91
            |..|.:|:   ::|::.|.:.::.|::.:..|:||:|..|.|..:.||:.:
  Rat    51 LENLEKCKQLIQLSVANNRLVRMMGVAKLTQLRVLNLPHNSIGCMEGLKDLVHLEWLNLAGNNLK 115

  Fly    92 -------AETLEELWLSYNLIEKIKGLTGLKCLKVL---------------YISNNL-------- 126
                   ...|:.|.||.|.|.:|..::.|..||.|               |:..||
  Rat   116 TMEQINSCSALQHLDLSDNNIPQIGDVSKLTALKTLLLHGNIITSLRMAPAYLPRNLSILSLAEN 180

  Fly   127 -IKDWSEFNRLAEIESLEDLVVVGNPLSEGLDEPTWRAECIKRLPTIRKLDGEPVVLN 183
             |:|.:|.:.||.:..||.|.::.||             |:...|:|...|..|.:::
  Rat   181 EIRDLNEISFLASLSELEQLSIMNNP-------------CVMATPSIPGFDYRPYIVS 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	42/183 (23%)
		leucine-rich repeat	50..71	CDD:275380	4/23 (17%)
		leucine-rich repeat	95..116	CDD:275380	8/20 (40%)
		leucine-rich repeat	117..141	CDD:275380	11/47 (23%)
Cep97	NP_001100566.1	leucine-rich repeat	17..37	CDD:275380
		LRR_RI	<21..126	CDD:238064	14/74 (19%)
		leucine-rich repeat	38..59	CDD:275380	3/7 (43%)
		leucine-rich repeat	60..81	CDD:275380	3/20 (15%)
		LRR_8	80..136	CDD:290566	13/55 (24%)
		LRR_4	80..122	CDD:289563	8/41 (20%)
		leucine-rich repeat	82..103	CDD:275380	8/20 (40%)
		LRR_4	103..143	CDD:289563	7/39 (18%)
		leucine-rich repeat	104..125	CDD:275380	0/20 (0%)
		LRR_9	107..255	CDD:258718	29/132 (22%)
		leucine-rich repeat	126..149	CDD:275380	8/22 (36%)
		leucine-rich repeat	150..171	CDD:275380	2/20 (10%)
		leucine-rich repeat	172..196	CDD:275380	6/23 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900