DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8800 and Lrrcc1

DIOPT Version :9

Sequence 1:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_001094115.3	Gene:	Lrrcc1 / 266808	RGDID:	628722	Length:	1025	Species:	Rattus norvegicus

Alignment Length:	179	Identity:	59/179 - (32%)
Similarity:	86/179 - (48%)	Gaps:	42/179 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 MDSTLGTL-VQCERIS---------------MSTNMIEKIFGLSGMKCLKVLSLSRNYIKQISGL 88
            :||:|..: :.|..||               :|:|.|.:|.||:.:..|..|:||.|.|.::.||
  Rat    36 LDSSLHAINLHCNNISKITSIDHIWNLRHLDLSSNQISQIEGLNTLTKLCTLNLSCNLITRVEGL 100

  Fly    89 EAVAETLEELWLSYNLIEKIKGLT---GLKCLKVLYIS--NNLIKDWSEFNRLAE----IESLED 144
            ||:. .|..|.||||.|..:.||.   ||| .|:.||.  :|.|   ...:.|.:    :..|.:
  Rat   101 EALV-NLTRLNLSYNHISDLSGLIPLHGLK-YKLRYIDLHSNYI---DSIHHLLQCTVGLHFLTN 160

  Fly   145 LVV----VGNPLSEGLDEPTWRAECIKRLPTIRKLD-----GEPVVLNE 184
            |::    .|||:..   .|.:||..::.||.:|.||     ||||.|.|
  Rat   161 LILEKDGEGNPICL---VPGYRAIILQTLPQLRILDCKNIFGEPVSLEE 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	55/173 (32%)
		leucine-rich repeat	50..71	CDD:275380	9/35 (26%)
		leucine-rich repeat	95..116	CDD:275380	11/23 (48%)
		leucine-rich repeat	117..141	CDD:275380	6/29 (21%)
Lrrcc1	NP_001094115.3	PPP1R42	25..197	CDD:411060	53/168 (32%)
		leucine-rich repeat	40..61	CDD:275378	4/20 (20%)
		leucine-rich repeat	62..83	CDD:275378	6/20 (30%)
		leucine-rich repeat	84..105	CDD:275378	10/21 (48%)
		leucine-rich repeat	106..131	CDD:275378	12/25 (48%)
		leucine-rich repeat	132..145	CDD:275378	4/15 (27%)
		leucine-rich repeat	158..188	CDD:275380	9/32 (28%)
		Smc	426..>758	CDD:224117
		Smc	<639..1020	CDD:224117
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900