DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8800 and T05H4.3

DIOPT Version :9

Sequence 1:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_001343670.1	Gene:	T05H4.3 / 188149	WormBaseID:	WBGene00020266	Length:	1150	Species:	Caenorhabditis elegans

Alignment Length:	187	Identity:	46/187 - (24%)
Similarity:	80/187 - (42%)	Gaps:	34/187 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 KVIDLQFQWPPIEKMDSTL------GTLVQCERISMSTNMIEKIFGLSGMKCLKVLSLSRNYIKQ 84
            :|.||..:...:|..|..|      ..||..:.:|:..|.:..:..|:.:.|||:|..|.|:|.:
Worm   621 EVSDLMTRLTALELCDQKLTKLTGIQELVSLQFLSVRKNKLTSLKKLNRLPCLKLLDASFNHISK 685

  Fly    85 ISGL--------------------EAVAETLEELWLSYNLIEKIKGLTGLKCLKVLYISNNLIKD 129
            |..|                    :::..| ..|.|..|.|:.:||:.....|:..::::||:||
Worm   686 IEQLPSSLLHVDLSHNKLQTLVFCQSLGNT-RHLLLHRNQIKSMKGVESCVQLETFFVNDNLLKD 749

  Fly   130 WSEFNRLAEIESLEDLVVVGNPLS--EGLDEPTWRAECIKRLPTIRKLDGEPVVLNE 184
            .|:...|..:..|..|.:..|.||  ||     :|...::....:..||.:.:.|.|
Worm   750 KSDVELLKTMPKLTHLDMSNNILSSAEG-----YRPRVMQAAQFLISLDRQIIPLEE 801

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	41/170 (24%)
		leucine-rich repeat	50..71	CDD:275380	3/20 (15%)
		leucine-rich repeat	95..116	CDD:275380	6/20 (30%)
		leucine-rich repeat	117..141	CDD:275380	7/23 (30%)
T05H4.3	NP_001343670.1	leucine-rich repeat	69..91	CDD:275380
		leucine-rich repeat	92..113	CDD:275380
		leucine-rich repeat	114..135	CDD:275380
		leucine-rich repeat	136..157	CDD:275380
		leucine-rich repeat	158..181	CDD:275380
		leucine-rich repeat	182..206	CDD:275380
		leucine-rich repeat	629..650	CDD:275380	4/20 (20%)
		PLN00113	645..>1005	CDD:331614	40/163 (25%)
		leucine-rich repeat	651..672	CDD:275380	3/20 (15%)
		leucine-rich repeat	673..692	CDD:275380	8/18 (44%)
		leucine-rich repeat	693..714	CDD:275380	0/20 (0%)
		leucine-rich repeat	715..761	CDD:275380	14/46 (30%)
		leucine-rich repeat	762..815	CDD:275380	12/45 (27%)
		leucine-rich repeat	816..851	CDD:275380
		leucine-rich repeat	855..875	CDD:275380
		leucine-rich repeat	876..903	CDD:275380
		leucine-rich repeat	904..952	CDD:275380
		leucine-rich repeat	953..973	CDD:275380
		leucine-rich repeat	974..994	CDD:275380
		leucine-rich repeat	995..1019	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900