DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8800 and R02F11.4

DIOPT Version :9

Sequence 1:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_504289.1	Gene:	R02F11.4 / 178871	WormBaseID:	WBGene00019842	Length:	630	Species:	Caenorhabditis elegans

Alignment Length:	153	Identity:	52/153 - (33%)
Similarity:	84/153 - (54%)	Gaps:	17/153 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 KMDSTLGTLVQCERISMSTNMIEKIFGLSGMKCLKVLSLSRNYIKQISGL-EAVAETLEELWLSY 102
            |..:.||.....:.:.:|.|:||.....| :|.|::|:||.|::.:|..| :.||  |:.:.|:.
Worm   133 KETNQLGRFENLKILDLSNNLIEPPVSFS-LKNLEILNLSGNFLNEIPDLSKCVA--LQTISLAD 194

  Fly   103 NLIEKIKGLTGLKC---LKVLYISNNLIKDWSEFNRLAEIESLEDLVVVGNP-LSEGLDEPTWR- 162
            |.|..:..:|.|.|   ||.|.||:|.|:|.|:|:.|:..:.||:.||.||| ::..||...:.
Worm   195 NKISDLTTITKLICPTNLKNLDISSNSIEDLSQFSVLSTFKKLEEFVVAGNPSITSVLDSDLFDY 259

  Fly   163 -----AECIKRLPTIRKLDGEPV 180
                 |.|.::|.||   ||:.:
Worm   260 RSYIFACCSEQLHTI---DGQKI 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	52/151 (34%)
		leucine-rich repeat	50..71	CDD:275380	5/20 (25%)
		leucine-rich repeat	95..116	CDD:275380	6/20 (30%)
		leucine-rich repeat	117..141	CDD:275380	11/23 (48%)
R02F11.4	NP_504289.1	leucine-rich repeat	57..78	CDD:275380
		LRR_RI	<118..245	CDD:238064	40/114 (35%)
		leucine-rich repeat	122..143	CDD:275380	3/9 (33%)
		LRR_8	143..197	CDD:290566	18/56 (32%)
		leucine-rich repeat	144..164	CDD:275380	5/20 (25%)
		LRR_4	163..205	CDD:289563	14/43 (33%)
		leucine-rich repeat	165..186	CDD:275380	7/20 (35%)
		leucine-rich repeat	187..211	CDD:275380	7/23 (30%)
		leucine-rich repeat	212..236	CDD:275380	11/23 (48%)
		leucine-rich repeat	237..256	CDD:275380	9/18 (50%)
		DUF2730	<480..557	CDD:287743
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810