DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8800 and C06A8.6

DIOPT Version :9

Sequence 1:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_495634.1	Gene:	C06A8.6 / 174253	WormBaseID:	WBGene00015516	Length:	349	Species:	Caenorhabditis elegans

Alignment Length:	199	Identity:	54/199 - (27%)
Similarity:	87/199 - (43%)	Gaps:	40/199 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SKATTIK--EALKRWEEREQQNSLTAKVIDLQFQWPPIEKMDSTLGTLVQCERISMSTNMIEKIF 64
            :|.|.|:  :.|...|..|..::..||          ||.:|:.|    :.:|:.:..|.|..|.
Worm   130 NKITKIEGLDTLTELEYLELGDNRIAK----------IENLDNNL----KLDRLFLGANQIRLIE 180

  Fly    65 GLSGMKCLKVLSLSRN---YIKQISGLEAVAE------------------TLEELWLSYNLIEKI 108
            .:..:|.|.||||..|   .:..||||..:.|                  .||.|..:.|.:||:
Worm   181 NVDHLKKLTVLSLPANAITVVDNISGLHNLKEIYLAQNGIKYVCGIDEHLPLEILDFNQNRLEKV 245

  Fly   109 KGLTGLKCLKVLYISNNLIKDWSEFNRLAEIESLEDLVVVGNPLSEGLDEPTWRAECIKRLPTIR 173
            :.:..||.|...:...|.:.:||..:.|.|:..|..:.:..||:: .:|  |:|.:.|..|..|.
Worm   246 ENIHQLKTLTDFWARGNKLDNWSIMDELVELPQLNSVYLDFNPIA-SVD--TYRGKVIHLLQQIT 307

  Fly   174 KLDG 177
            :|||
Worm   308 RLDG 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	46/162 (28%)
		leucine-rich repeat	50..71	CDD:275380	4/20 (20%)
		leucine-rich repeat	95..116	CDD:275380	7/20 (35%)
		leucine-rich repeat	117..141	CDD:275380	6/23 (26%)
C06A8.6	NP_495634.1	internalin_A	2..>279	CDD:380193	42/162 (26%)
		leucine-rich repeat	35..55	CDD:275380
		leucine-rich repeat	56..77	CDD:275380
		leucine-rich repeat	78..99	CDD:275380
		leucine-rich repeat	100..121	CDD:275380
		leucine-rich repeat	122..143	CDD:275380	4/12 (33%)
		leucine-rich repeat	144..165	CDD:275380	8/34 (24%)
		leucine-rich repeat	166..187	CDD:275380	4/20 (20%)
		leucine-rich repeat	188..209	CDD:275380	10/20 (50%)
		leucine-rich repeat	210..230	CDD:275380	1/19 (5%)
		leucine-rich repeat	232..278	CDD:275380	14/45 (31%)
		LRRcap	293..310	CDD:197729	6/18 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810