DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8800 and DNAAF1

DIOPT Version :9

Sequence 1:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	XP_011521155.1	Gene:	DNAAF1 / 123872	HGNCID:	30539	Length:	772	Species:	Homo sapiens

Alignment Length:	175	Identity:	54/175 - (30%)
Similarity:	89/175 - (50%)	Gaps:	19/175 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RWEEREQQNSLTAKVIDLQFQWPPIEKMDS-TLGTLVQCERISMSTNMIEKIFGLSGMKCLKVLS 76
            |.|..|:...|..    |..|...|:|::: ...|.::|  :.:..|::.||..|..::.|..|:
Human   121 RIENLEEYTGLRC----LWLQSNGIQKIENLEAQTELRC--LFLQMNLLRKIENLEPLQKLDALN 179

  Fly    77 LSRNYIKQISGLEAVAETLEELWLSYNLIEKIKGLTGL-KCLK--VLYISNNLIKDWSEFNRLAE 138
            ||.||||.|..|..: ..|..|.:::|.:|.::.:..| :||:  ||.:|:|.:.| .|.  |:.
Human   180 LSNNYIKTIENLSCL-PVLNTLQMAHNHLETVEDIQHLQECLRLCVLDLSHNKLSD-PEI--LSI 240

  Fly   139 IESLEDLVV---VGNPLSEGLDEPTWRAECIKRLPTIRKLDGEPV 180
            :||:.||.|   :|||:...:  |.:|.....||..:..||..||
Human   241 LESMPDLRVLNLMGNPVIRQI--PNYRRTVTVRLKHLTYLDDRPV 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	46/149 (31%)
		leucine-rich repeat	50..71	CDD:275380	5/20 (25%)
		leucine-rich repeat	95..116	CDD:275380	5/21 (24%)
		leucine-rich repeat	117..141	CDD:275380	8/25 (32%)
DNAAF1	XP_011521155.1	leucine-rich repeat	111..130	CDD:275380	3/8 (38%)
		LRR_4	129..171	CDD:289563	11/47 (23%)
		LRR_8	151..207	CDD:290566	19/58 (33%)
		LRR_4	151..192	CDD:289563	15/42 (36%)
		leucine-rich repeat	153..174	CDD:275380	5/22 (23%)
		LRR_4	173..215	CDD:289563	14/42 (33%)
		leucine-rich repeat	175..196	CDD:275380	10/21 (48%)
		LRR_8	195..257	CDD:290566	21/64 (33%)
		leucine-rich repeat	197..221	CDD:275380	6/23 (26%)
		LRR_4	221..263	CDD:289563	15/46 (33%)
		leucine-rich repeat	222..243	CDD:275380	7/23 (30%)
		leucine-rich repeat	247..274	CDD:275380	9/28 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810