DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8800 and drc3

DIOPT Version :9

Sequence 1:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_001123832.1	Gene:	drc3 / 100170587	XenbaseID:	XB-GENE-1003585	Length:	522	Species:	Xenopus tropicalis

Alignment Length:	158	Identity:	51/158 - (32%)
Similarity:	79/158 - (50%)	Gaps:	7/158 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 VIDLQFQWPPIEKMDSTLGTLVQCERISMSTNMIEKIFGLSGMKCLKVLSLSRNYIKQISGLEAV 91
            |..|:..:..|.|:|: |.......::.:..|:||||.||..:..|..|.||.|.|:.|.||:|:
Frog    45 VSSLRLDFKNILKIDN-LWQFHSLTKLQLDNNIIEKISGLDTLVHLVWLDLSFNNIEVIEGLKAL 108

  Fly    92 AETLEELWLSYNLIEKIKGLTGLKCLKVLYISNNLIKDWSEFNRLAEIESLEDLVVVGNPLSEGL 156
            .: ||:|.|..|.|..::.:..|..|:||.:.||.:........|.:.:.|..|.:.||||||
Frog   109 TK-LEDLSLYNNRISVVENMDTLSNLQVLSLGNNNLTSLENLIYLRKFKQLRTLSLAGNPLSE-- 170

  Fly   157 DEPTWRAECIKRLPTIRKLDGEPVVLNE 184
             :..::......||.:..||..  :|||
Frog   171 -DDQYKLFIAAHLPNLAYLDFR--LLNE 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	46/142 (32%)
		leucine-rich repeat	50..71	CDD:275380	7/20 (35%)
		leucine-rich repeat	95..116	CDD:275380	7/20 (35%)
		leucine-rich repeat	117..141	CDD:275380	6/23 (26%)
drc3	NP_001123832.1	leucine-rich repeat	47..66	CDD:275380	5/19 (26%)
		LRR_RI	<60..211	CDD:238064	46/143 (32%)
		leucine-rich repeat	67..88	CDD:275378	7/20 (35%)
		LRR_8	88..143	CDD:290566	22/55 (40%)
		leucine-rich repeat	89..110	CDD:275378	10/20 (50%)
		LRR_4	109..149	CDD:289563	12/40 (30%)
		leucine-rich repeat	111..132	CDD:275378	7/20 (35%)
		leucine-rich repeat	133..157	CDD:275378	6/23 (26%)
		leucine-rich repeat	158..169	CDD:275378	5/10 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910